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FcRH5/FcRL5 Protein, Human, Recombinant (His)

(Synonyms: IFGP5, FcR-like protein 5, FcRL5, FcRH5, CD307e, CD307, BXMAS1) Copy Product Info

Synonyms: IFGP5, FcR-like protein 5, FcRL5, FcRH5, CD307e, CD307, BXMAS1

Catalog No. TMPK-00618 Copy Product Info
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. FcRH5/FcRL5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 92.38 kDa and the accession number is AAK93971.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$68-In Stock
10 µg$108-In Stock
20 µg$177-In Stock
50 µg$346-In Stock
100 µg$581-In Stock
200 µg$1,0507-10 days7-10 days
500 µg$2,3307-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Appearance:Solution
Color:Transparent
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Product Introduction

Bioactivity
Bioactivity
Immobilized Human FcRH5, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Anti-FcRH5 Antibody, hFc Tag with the EC50 of 21.1ng/ml determined by ELISA.
Description
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. FcRH5/FcRL5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 92.38 kDa and the accession number is AAK93971.
Species
Human
Expression System
HEK293 Cells
TagC-His
Accession NumberAAK93971
ConstructionGln16-Gly851
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsIFGP5, FcR-like protein 5, FcRL5, FcRH5, CD307e, CD307, BXMAS1
Research Background
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent.
Chemical Properties
Molecular Weight92.38 kDa (predicted). Due to glycosylation, the protein migrates to 120-140 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

Related Tags: FcRH5/FcRL5 Protein, Human, Recombinant (His) chemical structure | FcRH5/FcRL5 Protein, Human, Recombinant (His) molecular weight