FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 581.00 | |
500 μg | 5 days | $ 2,330.00 | |
1 mg | 5 days | $ 3,880.00 |
Description | FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. |
Species | Human |
Expression System | HEK293 |
Tag | C-His |
Accession Number | AAK93971 |
Synonyms | FcR-like protein 5, CD307, BXMAS1, FcRH5, IFGP5, CD307e, FcRL5 |
Construction | Recombinant Human FcRH5/FcRL5 Protein is expressed from HEK293 with His tag at the C-Terminus. It contains Gln16-Gly851.[Accession |AAK93971] |
Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
Molecular Weight | The protein has a predicted MW of 92.38 kDa. Due to glycosylation, the protein migrates to 120-140 kDa based on Tris-Bis PAGE result. |
Endotoxin | Less than 1EU per μg by the LAL method. |
Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability & Storage |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. |
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Please read the User Guide of Recombinant Proteins for more specific information.
FcRH5/FcRL5 Protein, Human, Recombinant (His) FcR-like protein 5 CD307 IFGP-5 BXMAS1 BXMAS-1 CD-307 CD 307 BXMAS 1 FcRH5 IFGP5 IFGP 5 CD307e FcRL5 recombinant recombinant-proteins proteins protein