Shopping Cart
- Remove All
Your shopping cart is currently empty
Anti-Phospho-GSK3 beta (Ser9) Antibody (7D812)
😃Good
Catalog No. TMAY-01513
Alias Phospho-GSK3 beta (S9), p-GSK3 beta (Ser9), p-GSK3 beta (S9), GSK3 beta (p-Ser9), GSK3 beta (p-S9)
Anti-Phospho-GSK3 beta (Ser9) Antibody (7D812) is a Rabbit antibody targeting Phospho-GSK3 beta (Ser9). Anti-Phospho-GSK3 beta (Ser9) Antibody (7D812) can be used in WB.
Anti-Phospho-GSK3 beta (Ser9) Antibody (7D812)
Anti-Phospho-GSK3 beta (Ser9) Antibody (7D812)
😃Good
Catalog No. TMAY-01513Alias Phospho-GSK3 beta (S9), p-GSK3 beta (Ser9), p-GSK3 beta (S9), GSK3 beta (p-Ser9), GSK3 beta (p-S9)
Anti-Phospho-GSK3 beta (Ser9) Antibody (7D812) is a Rabbit antibody targeting Phospho-GSK3 beta (Ser9). Anti-Phospho-GSK3 beta (Ser9) Antibody (7D812) can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $82 | 7-10 days | |
| 100 μL | $234 | 7-10 days |
Bulk & Custom
Add to Cart
Questions
View MoreContact us for more batch information
Resource Download
Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: WB Reactivity: Human |
| Alias | Phospho-GSK3 beta (S9), p-GSK3 beta (Ser9), p-GSK3 beta (S9), GSK3 beta (p-Ser9), GSK3 beta (p-S9) |
| Ig Type | Rabbit IgG |
| Clone | 7D812 |
| Reactivity | Human;
Species predicted to react based on 100% sequence homology: mouse, rat |
| Verified Activity | 1. Western blot analysis of extracts from serum-starved Hela treated with calyculin A (100nM, 30 min), using Phospho-GSK3 beta (Ser9) Antibody, Rabbit MAb at 1:1000, 1:10000, 1:200000 dilution. (Validation Experiment) 2. Western blot analysis of extracts from serum-starved Hela, untreated (-) or treated with Calyculin A (100 nM, 30 min; +), using Phospho-GSK3 beta (Ser9) rabbit monoclonal Antibody at 1:1000 dilution. |
| Application | WB |
| Recommended Dose | WB: 1:1000-1:5000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to residues around Ser9 of Human Phospho-GSK3 beta. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | GSK3B is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It Contains 1 protein kinase domain, and is expressed in the testis, thymus, prostate, and ovary and weakly expressed in the lung, brain, and kidney. GSK3B is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in the GSK3B gene have been implicated in modifying the risk of Parkinson's disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer's disease. GSK3B participates in the Wnt signaling pathway. It is implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB, and the transcription factor JUN. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates MUC1 in breast cancer cells, and decreases the interaction of MUC1 with CTNNB1/beta-catenin. GSK3B also plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It prevents the phosphorylation of APC and CLASP2, allowing its association with the cell membrane. In turn, membrane-bound APC allows the localization of MACF1 to the cell membrane, which is required for microtubule capture and stabilization. GSK3B phosphorylates MACF1 and this phosphorylation inhibits the binding of MACF1 to microtubules which are critical for its role in bulge stem cell migration and skin wound repair. It may be required for early embryo development and neuron differentiation. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide corresponding to residues around Ser9 of Human Phospho-GSK3 beta |
| Antigen Species | Human |
| Biology Area | Notch Pathway |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
Sci Citations
Calculator
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Anti-Phospho-GSK3 beta (Ser9) Antibody (7D812) | purchase Anti-Phospho-GSK3 beta (Ser9) Antibody (7D812) | Anti-Phospho-GSK3 beta (Ser9) Antibody (7D812) cost | order Anti-Phospho-GSK3 beta (Ser9) Antibody (7D812)
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.