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Anti-Phospho-GSK3B (Tyr216) Polyclonal Antibody
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Catalog No. TMAB-01417
Alias p-GSK3B (Y216), p-GSK3B (Tyr216), GSK-3β, GSK3β, GSK3B (p-Y216), GSK3B (p-Tyr216), glycogen synthase kinase 3 β, glycogen synthase kinase 3 beta
Anti-Phospho-GSK3B (Tyr216) Polyclonal Antibody is a Rabbit antibody targeting Phospho-GSK3B (Tyr216). Anti-Phospho-GSK3B (Tyr216) Polyclonal Antibody can be used in WB.
Anti-Phospho-GSK3B (Tyr216) Polyclonal Antibody
Anti-Phospho-GSK3B (Tyr216) Polyclonal Antibody
😃Good
Catalog No. TMAB-01417Alias p-GSK3B (Y216), p-GSK3B (Tyr216), GSK-3β, GSK3β, GSK3B (p-Y216), GSK3B (p-Tyr216), glycogen synthase kinase 3 β, glycogen synthase kinase 3 beta
Anti-Phospho-GSK3B (Tyr216) Polyclonal Antibody is a Rabbit antibody targeting Phospho-GSK3B (Tyr216). Anti-Phospho-GSK3B (Tyr216) Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $222 | 7-10 days | |
| 100 μL | $374 | 7-10 days | |
| 200 μL | $529 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-GSK3B (Tyr216) Polyclonal Antibody is a Rabbit antibody targeting Phospho-GSK3B (Tyr216). Anti-Phospho-GSK3B (Tyr216) Polyclonal Antibody can be used in WB. |
| Alias | p-GSK3B (Y216), p-GSK3B (Tyr216), GSK-3β, GSK3β, GSK3B (p-Y216), GSK3B (p-Tyr216), glycogen synthase kinase 3 β, glycogen synthase kinase 3 beta |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,GuineaPig) |
| Verified Activity | Sample: Lane 1: Muscle (Mouse) Lysate at 40 μg Lane 2: Liver (Mouse) Lysate at 40 μg Lane 3: Cerebrum (Mouse) Lysate at 40 μg Lane 4: Pancreas (Mouse) Lysate at 40 μg Lane 5: Thymus (Mouse) Lysate at 40 μg Lane 6: Muscle (Rat) Lysate at 40 μg Lane 7: Liver (Rat) Lysate at 40 μg Lane 8: Cerebrum (Rat) Lysate at 40 μg Lane 9: Pancreas (Rat) Lysate at 40 μg Lane 10: Thymus (Rat) Lysate at 40 μg Lane 11: MCF-7 (Human) Cell Lysate at 30 μg Lane 12: A431 (Human) Cell Lysate at 30 μg Lane 13: U2os (Human) Cell Lysate at 30 μg Primary: Anti-phospho-GSK3 Alpha + Beta (Tyr279+Tyr216) (TMAB-01417) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 47/51 kDa Observed band size: 47 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Nucleus. Cell membrane. Note=The phosphorylated form shows localization to cytoplasm and cell membrane. The MEMO1-RHOA-DIAPH1 signaling pathway controls localization of the phosophorylated form to the cell membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009] |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human GSK-3 Beta around the phosphorylation site of Tyr216 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Integration of energy metabolism,Metabolism of carbohydrates,Diabetes associated,Hypertrophy,Carbohydrate metabolism,Integration of energy,Cancer,Diabetes,Heart disease,Notch Pathway,Other Kinases,Cytoplasmic,Cytoplasmic |
| Molecular Weight | Theoretical: 47 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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