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Beta-mammal toxin Css4 Protein, Centruroides suffusus, Recombinant (His & SUMO)

Catalog No. TMPH-00362
Synonyms: Css IV, CssIV, Beta-mammal toxin Css4

Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. This toxin is active only on mammals.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Beta-mammal toxin Css4 Protein, Centruroides suffusus, Recombinant (His & SUMO)
Pack Size Availability Price/USD Quantity
20 μg 20 days $ 360.00
100 μg 20 days $ 678.00
1 mg 20 days $ 2,300.00
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Biological Description
Technical Params
Product Properties
Description Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. This toxin is active only on mammals.
Species Centruroides suffusus
Expression System E. coli
Tag N-terminal 6xHis-SUMO-tagged
Accession Number P60266
Synonyms Css IV, CssIV, Beta-mammal toxin Css4
Amino Acid KEGYLVNSYTGCKFECFKLGDNDYCLRECRQQYGKGSGGYCYAFGCWCTHLYEQAVVWPLPNKTCN Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
Construction 20-85 aa
Protein Purity > 90% as determined by SDS-PAGE.
Molecular Weight 23.6 kDa (predicted)
Formulation Tris-based buffer,50% glycerol
Reconstitution A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. This toxin is active only on mammals.

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Keywords

Beta-mammal toxin Css4 Protein, Centruroides suffusus, Recombinant (His & SUMO) Css IV CssIV Beta-mammal toxin Css4 recombinant recombinant-proteins proteins protein

 

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