Shopping Cart

Your shopping cart is currently empty

Latanoprost acid

Name: Latanoprost acid
Brand: TargetMol
SKU: T15718
Price: 52 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T15718Cas No. 41639-83-2

Latanoprost acid is a selective agonist of prostanoid receptors and inhibits RANKL-induced osteoclastogenesis and function through the inhibition of c-fos/NFATc1 pathway. Latanoprost acid can be used in studies about lowering pressure inside the eyes.

Latanoprost acid

🥰Excellent

Purity: 97.96%

Catalog No. T15718Cas No. 41639-83-2

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$52	-	In Stock
5 mg	$148	-	In Stock
10 mg	$238	-	In Stock
25 mg	$477	-	In Stock
50 mg	$708	-	In Stock
100 mg	$972	-	In Stock
200 mg	$1,290	-	In Stock
1 mL x 10 mM (in DMSO)	$163	-	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:97.96%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Latanoprost acid is a selective agonist of prostanoid receptors and inhibits RANKL-induced osteoclastogenesis and function through the inhibition of c-fos/NFATc1 pathway. Latanoprost acid can be used in studies about lowering pressure inside the eyes.
In vitro	Latanoprost acid (10, 20 μM) reduces the protein expressions of c-fos and NFATc1 thus inhibiting the mature osteoclast formation in BMMs. Latanoprost acid (10μM) and RANKL(50ng/ml) significantly inhibit ERK, p38, AKT and JNK[1].
In vivo	Latanoprost acid (i.p.; 20 mg/kg; once daily for 7 days) effectively prevents LPS-induced bone destruction [1].

Chemical Properties

Molecular Weight	390.51
Formula	C₂₃H₃₄O₅
Cas No.	41639-83-2
Smiles	O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O)CCc1ccccc1
Relative Density.	1.159 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 27.5 mg/mL (70.42 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.12 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5608 mL	12.8038 mL	25.6075 mL	128.0377 mL
5 mM	0.5122 mL	2.5608 mL	5.1215 mL	25.6075 mL
10 mM	0.2561 mL	1.2804 mL	2.5608 mL	12.8038 mL
20 mM	0.1280 mL	0.6402 mL	1.2804 mL	6.4019 mL
50 mM	0.0512 mL	0.2561 mL	0.5122 mL	2.5608 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc