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Anti-CD8 beta Polyclonal Antibody
(Synonyms: P37, LYT3, LY3, Leu2, CD8B1, CD8b molecule, CD8 β) Copy Product Info
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Synonyms: P37, LYT3, LY3, Leu2, CD8B1, CD8b molecule, CD8 β
Catalog No. TMAB-00392 Copy Product Info
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Anti-CD8 beta Polyclonal Antibody is a Rabbit antibody targeting CD8 beta. Anti-CD8 beta Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Anti-CD8 beta Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CD8 beta Polyclonal Antibody is a Rabbit antibody targeting CD8 beta. Anti-CD8 beta Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P. |
| Synonyms | P37, LYT3, LY3, Leu2, CD8B1, CD8b molecule, CD8 β |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Chicken,Pig,Horse,GuineaPig) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Isoform 1, 2, 4, 5:Cell membrane; Single-pass type I membrane protein. Isoform 3, 6, 7, 8: Secreted. |
| Tissue Specificity | Isoform 1, isoform 3, isoform 5, isoform 6, isoform 7 and isoform 8 are expressed in both thymus and peripheral CD8+ T-cells. Expression of isoform 1 is higher in thymus CD8+ T-cells than in peripheral CD8+ T-cells. Expression of isoform 6 is higher in pe |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]. |
| Immunogen | KLH conjugated synthetic peptide: human CD8B |
| Antigen Species | Human |
| Gene Name | CD8B |
| Gene ID | |
| Protein Name | T-cell surface glycoprotein CD8 beta chain |
| Uniprot ID | |
| Biology Area | CD markers,CD |
| Function | Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. |
| Molecular Weight | Theoretical: 21 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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