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Suc-Ala-Glu-Pro-Phe-pNA

🥰Excellent
Catalog No. T87450Cas No. 128802-76-6
Alias Suc-AEPF-pNA

Suc-Ala-Glu-Pro-Phe-pNA is a chromogenic substrate for PPIase (peptidyl-prolyl cis-trans isomerase), which releases pNA with an absorbance of 390 nm upon binding to PPIase, enabling quantitative detection of Pin1 enzyme activity.

Suc-Ala-Glu-Pro-Phe-pNA

Suc-Ala-Glu-Pro-Phe-pNA

🥰Excellent
Purity: 99.11%
Catalog No. T87450Alias Suc-AEPF-pNACas No. 128802-76-6
Suc-Ala-Glu-Pro-Phe-pNA is a chromogenic substrate for PPIase (peptidyl-prolyl cis-trans isomerase), which releases pNA with an absorbance of 390 nm upon binding to PPIase, enabling quantitative detection of Pin1 enzyme activity.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$39-In Stock
5 mg$89-In Stock
10 mg$147-In Stock
25 mg$248-In Stock
50 mg$368-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.11%
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Product Introduction

Bioactivity
Description
Suc-Ala-Glu-Pro-Phe-pNA is a chromogenic substrate for PPIase (peptidyl-prolyl cis-trans isomerase), which releases pNA with an absorbance of 390 nm upon binding to PPIase, enabling quantitative detection of Pin1 enzyme activity.
SynonymsSuc-AEPF-pNA
Chemical Properties
Molecular Weight682.68
FormulaC32H38N6O11
Cas No.128802-76-6
SmilesC([C@@H](NC([C@@H](NC(CCC(O)=O)=O)C)=O)CCC(O)=O)(=O)N1[C@H](C(N[C@@H](CC2=CC=CC=C2)C(NC3=CC=C(N(=O)=O)C=C3)=O)=O)CCC1
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagekeep away from direct sunlight | store at -20°C | Shipping with blue ice.
Solubility Information
DMSO: 120 mg/mL (175.78 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.4648 mL7.3241 mL14.6482 mL73.2408 mL
5 mM0.2930 mL1.4648 mL2.9296 mL14.6482 mL
10 mM0.1465 mL0.7324 mL1.4648 mL7.3241 mL
20 mM0.0732 mL0.3662 mL0.7324 mL3.6620 mL
50 mM0.0293 mL0.1465 mL0.2930 mL1.4648 mL
100 mM0.0146 mL0.0732 mL0.1465 mL0.7324 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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