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Anti-EPAS1 Antibody (4H347)
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Catalog No. TMAH-00395
Alias PASD2, PAS domain-containing protein 2, MOP2, Member of PAS protein 2, Hypoxia-inducible factor 2-alpha, HLF, HIF2-alpha, HIF-2-alpha, HIF2A, HIF-1-alpha-like factor, EPAS-1, Endothelial PAS domain-containing protein 1, Class E basic helix-loop-helix protein 73, bHLHe73, Basic-helix-loop-helix-PAS protein MOP2
Anti-EPAS1 Antibody (4H347) is an antibody targeting EPAS1. Anti-EPAS1 Antibody (4H347) can be used in ELISA, IF.
Anti-EPAS1 Antibody (4H347)
Anti-EPAS1 Antibody (4H347)
😃Good
Catalog No. TMAH-00395Alias PASD2, PAS domain-containing protein 2, MOP2, Member of PAS protein 2, Hypoxia-inducible factor 2-alpha, HLF, HIF2-alpha, HIF-2-alpha, HIF2A, HIF-1-alpha-like factor, EPAS-1, Endothelial PAS domain-containing protein 1, Class E basic helix-loop-helix protein 73, bHLHe73, Basic-helix-loop-helix-PAS protein MOP2
Anti-EPAS1 Antibody (4H347) is an antibody targeting EPAS1. Anti-EPAS1 Antibody (4H347) can be used in ELISA, IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | 198 € | 7-10 days | |
| 100 μL | 331 € | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Recombinant Monoclonal Application: ELISA, IF Reactivity: Human |
| Alias | PASD2, PAS domain-containing protein 2, MOP2, Member of PAS protein 2, Hypoxia-inducible factor 2-alpha, HLF, HIF2-alpha, HIF-2-alpha, HIF2A, HIF-1-alpha-like factor, EPAS-1, Endothelial PAS domain-containing protein 1, Class E basic helix-loop-helix protein 73, bHLHe73, Basic-helix-loop-helix-PAS protein MOP2 |
| Ig Type | Rabbit IgG |
| Clone | 4H347 |
| Reactivity | Human |
| Verified Activity | Immunofluorescence staining of Hela Cells with TMAH-00395 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L). |
| Application | ELISA, IF |
| Recommended Dose | IF:1:20-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Nucleus. Nucleus speckle. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation requires recruitment of transcriptional coactivators such as CREBBP and probably EP300. Interaction with redox regulatory protein APEX1 seems to activate CTAD. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human HIF-2 alpha |
| Antigen Species | Human |
| Gene ID | 2034 |
| Uniprot ID | |
| Biology Area | Epigenetics and Nuclear Signaling, Cancer, Cardiovascular, Metabolism |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
Sci Citations
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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