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Anti-EPAS1 Antibody (4H347) (Synonyms: PASD2, PAS domain-containing protein 2, MOP2, Member of PAS protein 2|...)
Catalog No. TMAH-00395 Copy Product Info
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Anti-EPAS1 Antibody (4H347) is an antibody targeting EPAS1. Anti-EPAS1 Antibody (4H347) can be used in ELISA,IF.
Anti-EPAS1 Antibody (4H347)
Copy Product Info🥰Excellent
Catalog No. TMAH-00395
Synonyms PASD2, PAS domain-containing protein 2, MOP2, Member of PAS protein 2, Hypoxia-inducible factor 2-alpha, HLF, HIF2-alpha, HIF-2-alpha, HIF2A, HIF-1-alpha-like factor, EPAS-1, Endothelial PAS domain-containing protein 1, Class E basic helix-loop-helix protein 73, bHLHe73, Basic-helix-loop-helix-PAS protein MOP2
Anti-EPAS1 Antibody (4H347) is an antibody targeting EPAS1. Anti-EPAS1 Antibody (4H347) can be used in ELISA,IF.
Anti-EPAS1 Antibody
(4H347)
(4H347)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $349 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-EPAS1 Antibody (4H347) is an antibody targeting EPAS1. Anti-EPAS1 Antibody (4H347) can be used in ELISA,IF. |
| Synonyms | PASD2, PAS domain-containing protein 2, MOP2, Member of PAS protein 2, Hypoxia-inducible factor 2-alpha, HLF, HIF2-alpha, HIF-2-alpha, HIF2A, HIF-1-alpha-like factor, EPAS-1, Endothelial PAS domain-containing protein 1, Class E basic helix-loop-helix protein 73, bHLHe73, Basic-helix-loop-helix-PAS protein MOP2 |
| Ig Type | Rabbit IgG |
| Clone | 4H347 |
| Reactivity | Human |
| Verified Activity | Immunofluorescence staining of Hela Cells with TMAH-00395 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L). |
| Application | |
| Recommended Dose | IF:1:20-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Nucleus. Nucleus speckle. |
| Tissue Specificity | Expressed in most tissues, with highest levels in placenta, lung and heart. Selectively expressed in endothelial cells. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT; heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation requires recruitment of transcriptional coactivators such as CREBBP and probably EP300. Interaction with redox regulatory protein APEX1 seems to activate CTAD. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human HIF-2 alpha |
| Antigen Species | Human |
| Gene Name | EPAS1 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Epigenetics and Nuclear Signaling, Cancer, Cardiovascular, Metabolism |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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