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Anti-FOXO1 Polyclonal Antibody
(Synonyms: FOXO1A, Forkhead, Drosophila, homolog of, in rhabdomyosarcoma, Forkhead(Drosophila) homolog 1(rhabdomyosarcoma), Forkhead in rhabdomyosarcoma, Forkhead box protein O1A, Forkhead box protein O1, Forkhead box O1, Forkhead, Fkhr1, FKHR, FKH1, FKH 1, AI876417, Afxh) Copy Product Info
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Synonyms: FOXO1A, Forkhead, Drosophila, homolog of, in rhabdomyosarcoma, Forkhead(Drosophila) homolog 1(rhabdomyosarcoma), Forkhead in rhabdomyosarcoma, Forkhead box protein O1A, Forkhead box protein O1, Forkhead box O1, Forkhead, Fkhr1, FKHR, FKH1, FKH 1, AI876417, Afxh
Catalog No. TMAB-00707 Copy Product Info
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Anti-FOXO1 Polyclonal Antibody is a Rabbit antibody targeting FOXO1. Anti-FOXO1 Polyclonal Antibody can be used in FCM, IF, IHC-Fr, IHC-P, WB.
Anti-FOXO1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
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Antigen Details
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| Description | Anti-FOXO1 Polyclonal Antibody is a Rabbit antibody targeting FOXO1. Anti-FOXO1 Polyclonal Antibody can be used in FCM, IF, IHC-Fr, IHC-P, WB. |
| Synonyms | FOXO1A, Forkhead, Drosophila, homolog of, in rhabdomyosarcoma, Forkhead(Drosophila) homolog 1(rhabdomyosarcoma), Forkhead in rhabdomyosarcoma, Forkhead box protein O1A, Forkhead box protein O1, Forkhead box O1, Forkhead, Fkhr1, FKHR, FKH1, FKH 1, AI876417, Afxh |
| Ig Type | IgG |
| Reactivity | Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit) |
| Application | |
| Recommended Dose | FCM=2 μg/Test; IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; WB=1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Nucleus. Note=Shuttles between cytoplasm and nucleus. Translocates to the nucleus upon oxidative stress induced phosphorylation at Ser-212 by STK4/MST1. Translocates to the nucleus upon phosphorylation of Thr-24, Ser-256 and Ser-322 by SGK1. |
| Tissue Specificity | Ubiquitous. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. [provided by RefSeq]. |
| Immunogen | KLH conjugated synthetic peptide: human FOXO1 |
| Antigen Species | Human |
| Gene Name | FOXO1 |
| Gene ID | |
| Protein Name | Forkhead box protein O1 |
| Uniprot ID | |
| Biology Area | Coactivators and repressors,Co-activators/co-repressors,FOXO,Obesity,Neurogenesis,Co-activators/co-repressors |
| Function | Transcription factor which acts as a regulator of cell responses to oxidative stress. In the presence of KIRT1, mediates down-regulation of cyclin D1 and up-regulation of CDKN1B levels which are required for cell transition from proliferative growth to quiescence. Triggers death of postmitotic neurons when phosphorylated by CDK1. Activates transcription of PMAIP1. |
| Molecular Weight | Theoretical: 70 kDa. Actual: 75 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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