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Anti-APC Antibody (2Z81)
(Synonyms: Protein APC, DP2.5, Deleted in polyposis 2.5, Adenomatous polyposis coli protein) Copy Product Info
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Synonyms: Protein APC, DP2.5, Deleted in polyposis 2.5, Adenomatous polyposis coli protein
Catalog No. TMAH-00068 Copy Product Info
🥰Excellent
Anti-APC Antibody (2Z81) is an antibody targeting APC. Anti-APC Antibody (2Z81) can be used in ELISA,IHC,WB.
Anti-APC Antibody
(2Z81)
(2Z81)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $208 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-APC Antibody (2Z81) is an antibody targeting APC. Anti-APC Antibody (2Z81) can be used in ELISA,IHC,WB. |
| Synonyms | Protein APC, DP2.5, Deleted in polyposis 2.5, Adenomatous polyposis coli protein |
| Ig Type | Rabbit IgG |
| Clone | 2Z81 |
| Reactivity | Human, Rat |
| Application | |
| Recommended Dose | WB:1:500-1:5000; IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cell junction, adherens junction. Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cell projection, ruffle membrane. Cytoplasm. Cell membrane. |
| Tissue Specificity | Expressed in a variety of tissues: brain, small intestine, colon, thymus, skeletal muscle, heart, prostate, lung, spleen, ovary, testis kidney, placenta, blood and liver. Isoform 1A: Very strongly expressed in brain but has relatively low expression level |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Tumor suppressor. Promotes rapid degradation of CTNNB1 and participates in Wnt signaling as a negative regulator. APC activity is correlated with its phosphorylation state. Activates the GEF activity of SPATA13 and ARHGEF4. Plays a role in hepatocyte growth factor (HGF)-induced cell migration. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Acts as a mediator of ERBB2-dependent stabilization of microtubules at the cell cortex. It is required for the localization of MACF1 to the cell membrane and this localization of MACF1 is critical for its function in microtubule stabilization. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human APC |
| Antigen Species | Human |
| Gene Name | APC |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Epigenetics and Nuclear Signaling, Neuroscience, Cancer, Cardiovascular, Cell biology, Stem cells |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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