5T4/TPBG Protein, Human, Recombinant (aa 60-345, His)

Catalog No. TMPY-05033 Copy Product Info

Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Human, Recombinant (aa 60-345, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.1 kDa and the accession number is Q13641.

5T4/TPBG Protein, Human, Recombinant (aa 60-345, His)

Catalog No. TMPY-05033

Copy Product Info

5T4/TPBG Protein, Human, Recombinant (aa 60-345, His)

Pack Size	Price	USA Stock	Global Stock
5 μg	$55	7-10 days	7-10 days
10 μg	$86	7-10 days	7-10 days
20 μg	$139	7-10 days	7-10 days
50 μg	$269	7-10 days	7-10 days
100 μg	$451	-	In Stock
200 μg	$797	7-10 days	7-10 days
500 μg	$1,680	7-10 days	7-10 days

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For In stock only · Estimated delivery:USA Stock (1-2 days) Global Stock (5-7 days)

For research use only—not for human use. No sales to individuals. Use as intended only.

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Biological Activity	1.Loaded anti-5T4/TPBG antibody, human IgG1 on proA Biosensor, can bind Recombinant Human 5T4/TPBG Protein, His Tag (Cat#TMPY-05033) with an affinity constant of 1.910 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested). 2.Immobilized Anti-5T4/TPBG antibody, human IgG1 at 2 μg/mL (100 μL/well) can bind Recombinant Human TPBG/5T4 Protein (His Tag) (Cat#TMPY-05033), the EC50 is 0.6-2.0 ng/mL (QC tested).
Description	Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Human, Recombinant (aa 60-345, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.1 kDa and the accession number is Q13641.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	Q13641
Synonyms	WAIF1,trophoblast glycoprotein,M6P1,5T4AG,5T4
Construction	A DNA sequence encoding the human TPBG (NP_006661.1) (Asp60-Asp345) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Asp 60
Protein Purity	≥ 95 % as determined by SDS-PAGE. ≥90 % as determined by SEC-HPLC.
Molecular Weight	33.1 kDa (predicted)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Research Background	Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues.