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5T4/TPBG Protein, Human, Recombinant (aa 60-345, His)
(Synonyms: WAIF1, trophoblast glycoprotein, M6P1, 5T4AG, 5T4) Copy Product InfoSynonyms: WAIF1, trophoblast glycoprotein, M6P1, 5T4AG, 5T4
Catalog No. TMPY-05033 Copy Product Info
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Human, Recombinant (aa 60-345, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.1 kDa and the accession number is Q13641.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $55 | - | In Stock | |
| 10 µg | $86 | - | In Stock | |
| 20 µg | $139 | - | In Stock | |
| 50 µg | $269 | - | In Stock | |
| 100 µg | $451 | - | In Stock | |
| 200 µg | $797 | 7-10 days | 7-10 days | |
| 500 µg | $1,680 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:SEC-HPLC: 98.6%
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | 1.Loaded anti-5T4/TPBG antibody, human IgG1 on proA Biosensor, can bind Recombinant Human 5T4/TPBG Protein, His Tag (Cat#TMPY-05033) with an affinity constant of 1.910 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested). 2.Immobilized Anti-5T4/TPBG antibody, human IgG1 at 2 μg/mL (100 μL/well) can bind Recombinant Human TPBG/5T4 Protein (His Tag) (Cat#TMPY-05033), the EC50 is 0.6-2.0 ng/mL (QC tested). |
| Description | Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Human, Recombinant (aa 60-345, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.1 kDa and the accession number is Q13641. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | Q13641 |
| Construction | A DNA sequence encoding the human TPBG (NP_006661.1) (Asp60-Asp345) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Asp 60 |
| Protein Purity | ≥ 95 % as determined by SDS-PAGE. ≥90 % as determined by SEC-HPLC.  , |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot. |
| Synonyms | WAIF1, trophoblast glycoprotein, M6P1, 5T4AG, 5T4 |
| Research Background | Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. |
| Molecular Weight | 33.1 kDa (predicted) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: 5T4/TPBG Protein, Human, Recombinant (aa 60-345, His) chemical structure | 5T4/TPBG Protein, Human, Recombinant (aa 60-345, His) molecular weight
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