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Anti-Phospho-BTK (Y223) Antibody (1E544)
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Catalog No. TMAC-03194
Anti-Phospho-BTK (Y223) Antibody (1E544) is a Rabbit antibody targeting Phospho-BTK (Y223). Anti-Phospho-BTK (Y223) Antibody (1E544) can be used in WB,IP.
Anti-Phospho-BTK (Y223) Antibody (1E544)
Anti-Phospho-BTK (Y223) Antibody (1E544)
😃Good
Catalog No. TMAC-03194
Anti-Phospho-BTK (Y223) Antibody (1E544) is a Rabbit antibody targeting Phospho-BTK (Y223). Anti-Phospho-BTK (Y223) Antibody (1E544) can be used in WB,IP.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $497 | 7-10 days |
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| Description | Anti-Phospho-BTK (Y223) Antibody (1E544) is a Rabbit antibody targeting Phospho-BTK (Y223). Anti-Phospho-BTK (Y223) Antibody (1E544) can be used in WB,IP. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:1000-2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The Tec family of non-receptor tyrosine kinases is composed of six proteins designated Tec, Emt (also known as Itk or Tsk), Btk (previously known as Atk, BPK or Emb), Bmx, Txk (also known as Rlk) and Dsrc28C. All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain a pleckstrin homology (PH) and a Tec homology (TH) domain in their amino termini. Four alternatively spliced forms of Tec are found to be expressed broadly in cells of hematopoietic lineage and hepatocytes. The Emt gene product associates with CD28 and becomes activated subsequent to CD28 ligation. Btk is necessary for proper B cell development, and mutations in the gene encoding Btk have been associated with families suffering from X-linked agammaglobulinemia, also referred to as Bruton’s disease. The Bmx protein shares a high degree of homology with Btk and seems to be expressed at highest levels in the heart. Txk expression is T cell-specific, while expression of the Drosophila Tec homolog, Dsrc28C, is developmentally regulated. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | A synthesized phosphopeptide: human BTK around the phosphorylation site of Tyr223 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 76 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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