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Anti-Phospho-HDAC3 (Ser424) Polyclonal Antibody
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Catalog No. TMAC-01776
Anti-Phospho-HDAC3 (Ser424) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HDAC3 (Ser424). Anti-Phospho-HDAC3 (Ser424) Polyclonal Antibody can be used in WB.
Anti-Phospho-HDAC3 (Ser424) Polyclonal Antibody
Anti-Phospho-HDAC3 (Ser424) Polyclonal Antibody
😃Good
Catalog No. TMAC-01776
Anti-Phospho-HDAC3 (Ser424) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HDAC3 (Ser424). Anti-Phospho-HDAC3 (Ser424) Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $217 | 7-10 days | |
| 100 μL | $318 | 7-10 days |
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Chemical Properties
| Description | Anti-Phospho-HDAC3 (Ser424) Polyclonal Antibody is a Rabbit antibody targeting Phospho-HDAC3 (Ser424). Anti-Phospho-HDAC3 (Ser424) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Probably participates in the regulation of transcription through its binding to the zinc-finger transcription factor YY1; increases YY1 repression activity. Required to repress transcription of the POU1F1 transcription factor. Acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of Serine 424 (K-E-S(p)-D-V) derived from Human HDAC3 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 48 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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