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Bovine Type II Collagen
🥰Excellent
Catalog No. T80025Cas No. 9007-34-5
Alias Collagen Type II,Bovine
Collagen, Type II (derived from bovine snout cartilage), is a homotrimeric helical protein composed of three identical α1(II) chains and is a major component of animal cartilage. It possesses multiple biological activities, including maintaining cartilage tissue integrity, inducing immune tolerance, and promoting chondrocyte growth and redifferentiation. It is commonly used to induce collagen-induced arthritis (CIA) models and has demonstrated significant efficacy in alleviating pain and inflammation associated with collagen-induced arthritis in mice, making it widely applicable in osteoarthritis-related research.
Bovine Type II Collagen
Bovine Type II Collagen
🥰Excellent
Catalog No. T80025Alias Collagen Type II,BovineCas No. 9007-34-5
Collagen, Type II (derived from bovine snout cartilage), is a homotrimeric helical protein composed of three identical α1(II) chains and is a major component of animal cartilage. It possesses multiple biological activities, including maintaining cartilage tissue integrity, inducing immune tolerance, and promoting chondrocyte growth and redifferentiation. It is commonly used to induce collagen-induced arthritis (CIA) models and has demonstrated significant efficacy in alleviating pain and inflammation associated with collagen-induced arthritis in mice, making it widely applicable in osteoarthritis-related research.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 mg | $40 | In Stock | In Stock | |
| 500 mg | $92 | In Stock | In Stock | |
| 1 g | $133 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Appearance:Solid
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Collagen, Type II (derived from bovine snout cartilage), is a homotrimeric helical protein composed of three identical α1(II) chains and is a major component of animal cartilage. It possesses multiple biological activities, including maintaining cartilage tissue integrity, inducing immune tolerance, and promoting chondrocyte growth and redifferentiation. It is commonly used to induce collagen-induced arthritis (CIA) models and has demonstrated significant efficacy in alleviating pain and inflammation associated with collagen-induced arthritis in mice, making it widely applicable in osteoarthritis-related research. |
| Synonyms | Collagen Type II,Bovine |
| Cas No. | 9007-34-5 |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility Information | H2O: 247.5 mg/mL, Sonication is recommended.  Acetic Acid: 20 mg/mL, Sonication is recommended. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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