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Bovine Type II Collagen
🥰Excellent
Catalog No. T80025Cas No. 9007-34-5
Alias Collagen Type II,Bovine
Collagen, Type II (derived from bovine snout cartilage), is a homotrimeric helical protein composed of three identical α1(II) chains and is a major component of animal cartilage. It possesses multiple biological activities, including maintaining cartilage tissue integrity, inducing immune tolerance, and promoting chondrocyte growth and redifferentiation. It is commonly used to induce collagen-induced arthritis (CIA) models and has demonstrated significant efficacy in alleviating pain and inflammation associated with collagen-induced arthritis in mice, making it widely applicable in osteoarthritis-related research.
Bovine Type II Collagen
Bovine Type II Collagen
🥰Excellent
Catalog No. T80025Alias Collagen Type II,BovineCas No. 9007-34-5
Collagen, Type II (derived from bovine snout cartilage), is a homotrimeric helical protein composed of three identical α1(II) chains and is a major component of animal cartilage. It possesses multiple biological activities, including maintaining cartilage tissue integrity, inducing immune tolerance, and promoting chondrocyte growth and redifferentiation. It is commonly used to induce collagen-induced arthritis (CIA) models and has demonstrated significant efficacy in alleviating pain and inflammation associated with collagen-induced arthritis in mice, making it widely applicable in osteoarthritis-related research.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 mg | $40 | In Stock | |
| 500 mg | $92 | In Stock | |
| 1 g | $133 | In Stock |
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Chemical Properties
| Description | Collagen, Type II (derived from bovine snout cartilage), is a homotrimeric helical protein composed of three identical α1(II) chains and is a major component of animal cartilage. It possesses multiple biological activities, including maintaining cartilage tissue integrity, inducing immune tolerance, and promoting chondrocyte growth and redifferentiation. It is commonly used to induce collagen-induced arthritis (CIA) models and has demonstrated significant efficacy in alleviating pain and inflammation associated with collagen-induced arthritis in mice, making it widely applicable in osteoarthritis-related research. |
| Synonyms | Collagen Type II,Bovine |
| Cas No. | 9007-34-5 |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Solubility Information | H2O: 80 mg/mL, Sonication is recommended. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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