BAFFR/TNFRSF13C Protein, Rat, Recombinant (hFc)

Name: BAFFR/TNFRSF13C Protein, Rat, Recombinant (hFc)
Brand: TargetMol
SKU: TMPY-03909
Rating: 4.5 (1 reviews)

(Synonyms: tumor necrosis factor receptor superfamily, member 13C) Copy Product Info

Synonyms: tumor necrosis factor receptor superfamily, member 13C

Catalog No. TMPY-03909 Copy Product Info

BAFFR/TNFRSF13C Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33.8 kDa and the accession number is D4A281.

Pack Size	Price	EUR Stock	Global Stock
5 µg	61 €	7-10 days	7-10 days
10 µg	97 €	7-10 days	7-10 days
20 µg	160 €	7-10 days	7-10 days
50 µg	323 €	7-10 days	7-10 days
100 µg	626 €	7-10 days	7-10 days

For In stock only · Estimated delivery: EUR Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Information

Bioactivity

Bioactivity	Immobilized human BAFF at 10 μg/ml (100 μl/well) can bind rat TNFRSF13C-Fc, The EC50 of rat TNFRSF13C-Fc is 0.02-0.06 μg/ml.
Description	BAFFR/TNFRSF13C Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33.8 kDa and the accession number is D4A281.
Species	Rat
Expression System	HEK293 Cells
Tag	C-hFc
Accession Number	D4A281
Construction	A DNA sequence encoding the rat TNFRSF13C (XP_576316.2) (Ser10-Ala71) was expressed with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Ser 10
Protein Purity	> 90 % as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	tumor necrosis factor receptor superfamily, member 13C
Research Background	Tumor necrosis factor receptor superfamily, member 13C (TNFRSF13C) also known as B-cell-activating factor receptor (BAFFR) and CD268 antigen, is a member of the tumor necrosis factor receptor superfamily. A tumor necrosis factor receptor (TNFR), or death receptor, is a trimeric cytokine receptor that binds tumor necrosis factors (TNF). The receptor cooperates with an adaptor protein which is important in determining the outcome of the response. Members of the TNF receptor superfamily (TNFRSF) have crucial roles in both innate and adaptive immunity and in cellular apoptosis process. Apoptosis is a cell suicide mechanism that enables metazoans to control cell number in tissues and to eliminate individual cells that threaten the animal's survival. Certain cells have unique sensors, termed death receptors or tumour necrosis factor (TNFR), on their surface. Tumour necrosis factors (TNFR) detect the presence of extracellular death signals and, in response, they rapidly ignite the cell's intrinsic apoptosis machinery. It has been proposed that abnormally high levels of BAFFR/TNFRSF13C (CD268) may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells.

Chemical Properties

Molecular Weight

33.8 kDa (predicted); 42 kDa (reducing condition, due to glycosylation)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.