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Efonidipine

Name: Efonidipine
Brand: TargetMol
SKU: T2323
Price: 35 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T2323Cas No. 111011-63-3

Alias NZ-105, (±)-Efonidipine

Efonidipine (NZ-105)(NZ-105) is a dihydropyridine calcium channel blocker, blocking both T-type and L-type calcium channels.

Efonidipine

🥰Excellent

Purity: 99.47%

Catalog No. T2323Alias NZ-105, (±)-EfonidipineCas No. 111011-63-3

Efonidipine (NZ-105)(NZ-105) is a dihydropyridine calcium channel blocker, blocking both T-type and L-type calcium channels.

Pack Size	Price	Availability
5 mg	$35	In Stock
10 mg	$58	In Stock
25 mg	$112	In Stock
50 mg	$179	In Stock
100 mg	$289	In Stock
200 mg	$433	In Stock
1 mL x 10 mM (in DMSO)	$50	In Stock

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Purity:99.47%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Efonidipine (NZ-105)(NZ-105) is a dihydropyridine calcium channel blocker, blocking both T-type and L-type calcium channels.
Synonyms	NZ-105, (±)-Efonidipine

Chemical Properties

Molecular Weight	631.66
Formula	C₃₄H₃₈N₃O₇P
Cas No.	111011-63-3
Smiles	C(OCCN(CC1=CC=CC=C1)C2=CC=CC=C2)(=O)C=3C(C(=C(C)NC3C)P4(=O)OCC(C)(C)CO4)C5=CC(N(=O)=O)=CC=C5
Relative Density.	1.3g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 22.5 mg/mL (35.62 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.5831 mL	7.9157 mL	15.8313 mL	79.1565 mL
5 mM	0.3166 mL	1.5831 mL	3.1663 mL	15.8313 mL
10 mM	0.1583 mL	0.7916 mL	1.5831 mL	7.9157 mL
20 mM	0.0792 mL	0.3958 mL	0.7916 mL	3.9578 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc