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Claudin-18.2 Protein, Human, Recombinant (His & Avi), Biotinylated

(Synonyms: CLDN18, Claudin-18) Copy Product Info

Synonyms: CLDN18, Claudin-18

Catalog No. TMPJ-01027 Copy Product Info
Claudin-18.2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-6xHis and C-Avi tag. The predicted molecular weight is 13 KDa and the accession number is P56856-2.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$189-In Stock
10 μg$318-In Stock
20 μg$53335 days35 days
50 μg$94235 days35 days
100 μg$1,45035 days35 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Batch Information

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Purity:≥95%
Appearance:Solution
Color:Transparent
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Claudin-18.2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-6xHis and C-Avi tag. The predicted molecular weight is 13 KDa and the accession number is P56856-2.
Species
Human
Expression System
E. coli
TagN-6xHis, C-Avi
Accession NumberP56856-2
Amino Acidextracellular
Constructionextracellular
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationSupplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 8M Urea, 150 mM NaCl, 5 mM β-ME, pH 8.5.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingProteins are shipped with blue ice.
SynonymsCLDN18, Claudin-18
Research Background
Claudin-18(CLDN18) is a protein that in humans is encoded by the CLDN18 gene. It belongs to the group of claudins. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. CLDN18 plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. CLDN18 has two isoform A1 and isoform A2. IMAB362 (Claudiximab) is a monoclonal antibody against isoform 2 of Claudin-18. It is under investigation for the treatment of gastrointestinal adenocarcinomas and pancreatic tumors. IMAB362 was developed by Ganymed Pharmaceuticals AG.
Chemical Properties
Molecular Weight13 KDa (reducing condition)
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Keywords

Related Tags: Claudin-18.2 Protein, Human, Recombinant (His & Avi), Biotinylated chemical structure | Claudin-18.2 Protein, Human, Recombinant (His & Avi), Biotinylated molecular weight