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Anti-FCGBP Polyclonal Antibody
(Synonyms: IgGFc-binding protein, Human Fc gamma BP, FCGBP, FcgammaBP, Fcgamma-binding protein antigen, FC(GAMMA)BP, Fc fragment of IgG binding protein) Copy Product Info
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Synonyms: IgGFc-binding protein, Human Fc gamma BP, FCGBP, FcgammaBP, Fcgamma-binding protein antigen, FC(GAMMA)BP, Fc fragment of IgG binding protein
Catalog No. TMAB-00665 Copy Product Info
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Anti-FCGBP Polyclonal Antibody is a Rabbit antibody targeting FCGBP. Anti-FCGBP Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P, WB.
Anti-FCGBP Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-FCGBP Polyclonal Antibody is a Rabbit antibody targeting FCGBP. Anti-FCGBP Polyclonal Antibody can be used in IF, IHC-Fr, IHC-P, WB. |
| Synonyms | IgGFc-binding protein, Human Fc gamma BP, FCGBP, FcgammaBP, Fcgamma-binding protein antigen, FC(GAMMA)BP, Fc fragment of IgG binding protein |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Dog,Rabbit) |
| Application | |
| Recommended Dose | IF=1:100-500; IHC-Fr=1:100-500; IHC-P=1:100-500; WB=1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Mainly expressed in placenta and colon epithelium. Expressed in thyroid, and down-regulated in thyroid carcinomas. Present in serum, with higher levels in patients with various autoimmune diseases (at protein level). |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Fc (Ig constant fragment) receptors ensure protection of the host against foreign antigens, such as microorganisms and pathogens, by removing Ig-coated antigen complexes from circulation. Fc receptors are present on lymphoid and myeloid derivatives, where they mediate endocytosis of Ig-antigen complexes, antibody production in B cells through T cell antigen presentation, cytotoxicity and the release of cytokines and reactive oxygen species. The Fc γ-binding protein (FCGBP) interacts with the Fc portion of IgG and MUC2 to mediate the maintenance of the mucosal structure. FCGBP is a 5,405 amino acid protein that contains twelve TIL (trypsin inhibitory-like) domains and thirteen VWFD domains. It is predominantly expressed in placenta and colon epithelium as well as in thyroid and serum. Patients with various autoimmune diseases seemingly have higher levels of FCGBP protein present in their serum. |
| Immunogen | KLH conjugated synthetic peptide: human FCGBP |
| Antigen Species | Human |
| Gene Name | FCGBP |
| Gene ID | |
| Protein Name | IgGFc-binding protein |
| Uniprot ID | |
| Biology Area | IgG,Receptors |
| Function | May be involved in the maintenance of the mucosal structure as a gel-like component of the mucosa. |
| Molecular Weight | Theoretical: 569 kDa. Actual: 120 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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