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Anti-CD59 Antibody-APC (6Z816)
🥰Excellent
Catalog No. TMAY-03805A
Anti-CD59 Antibody-APC (6Z816) is a APC-conjugated Rabbit antibody targeting CD59. Anti-CD59 Antibody-APC (6Z816) can be used in FCM.
Anti-CD59 Antibody-APC (6Z816)
Anti-CD59 Antibody-APC (6Z816)
🥰Excellent
Catalog No. TMAY-03805A
Anti-CD59 Antibody-APC (6Z816) is a APC-conjugated Rabbit antibody targeting CD59. Anti-CD59 Antibody-APC (6Z816) can be used in FCM.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD59 Antibody-APC (6Z816) is a APC-conjugated Rabbit antibody targeting CD59. Anti-CD59 Antibody-APC (6Z816) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 6Z816 |
| Reactivity | Rat |
| Verified Activity | Flow cytometric analysis of Rat CD59 expression on SD rat bone marrow cells. Cells were stained with APC-conjugated anti-Rat CD59. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM |
| Recommended Dose | 5 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Rat CD59 (rR CD59; TMPY-03091; P27274; Met1-Asn100) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | CD59 glycoprotein, also known as 2 kDa homologous restriction factor, HRF2, MAC-inhibitory protein, Membrane attack complex inhibition factor, Membrane inhibitor of reactive lysis, MIC11, MIRL and CD59, is a cell membrane protein which contains one UPAR/Ly6 domain. CD59 is a small, highly glycosylated, GPI-linked protein, with a wide expression profile. The soluble form of CD59 from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. CD59 is a potent inhibitor of the complement membrane attack complex (MAC) action. CD59 was first identified as a regulator of the terminal pathway of complement. It acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. CD59 is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. Defects in CD59 are the cause of CD59 deficiency (CD59D). |
| Conjucates | APC |
| Others Formats | Unconjugated/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Rat CD59 Protein (TMPY-03091) |
| Antigen Species | Rat |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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