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Anti-Phospho-Src (Tyr419) Antibody (2I773) is a Rabbit antibody targeting Phospho-Src (Tyr419). Anti-Phospho-Src (Tyr419) Antibody (2I773) can be used in FCM,WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $298 | 7-10 days | |
100 μL | $496 | 7-10 days |
Description | Anti-Phospho-Src (Tyr419) Antibody (2I773) is a Rabbit antibody targeting Phospho-Src (Tyr419). Anti-Phospho-Src (Tyr419) Antibody (2I773) can be used in FCM,WB. |
Synonyms | Src (p-Y419), Src (p-Tyr419), p-Src (Y419), p-Src (Tyr419) |
Ig Type | IgG |
Clone | 2I773 |
Reactivity | Human,Mouse,Rat |
Verified Activity | 1. Flow cytometric analysis of Hela cells with Phospho-Src (Y419) antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
Application | |
Recommended Dose | WB: 1:1000; FCM: 1:50-100 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | Recombinant Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | The Src family of protein tyrosine kinases, which includes Src, Lyn, Fyn, Yes, Lck, Blk, and Hck, are important in the regulation of growth and differentiation of eukaryotic cells. Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active. |
Conjucates | Unconjugated |
Others Formats | Phospho |
Immunogen | A synthesized phosphopeptide: human Src around the phosphorylation site of Tyr419 |
Antigen Species | human |
Uniprot ID |
Molecular Weight | Theoretical: 60 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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