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Zinc Alpha 2 Glycoprotein/AZGP1 Protein, Human, Recombinant (His)

(Synonyms: α-2-glycoprotein 1, zinc-binding, Zinc α 2, ZAG, ZA2G, alpha-2-glycoprotein 1, zinc-binding) Copy Product Info

Synonyms: α-2-glycoprotein 1, zinc-binding, Zinc α 2, ZAG, ZA2G, alpha-2-glycoprotein 1, zinc-binding

Catalog No. TMPY-03117 Copy Product Info
Alpha-2-glycoprotein, also known as AZGP1, belongs to the MHC class I family. It can be detected in body fluids such as serum, sweat, and seminal and breast cyst fluids. It has been shown that alpha-2-glycoprotein can stimulate lipolysis by adipocytes in vivo and in vitro. Thus it is believed that alpha-2-glycoprotein plays an important role in the regulation of body weight, and age-dependent changes in genetically influenced obesity, and it also regulates melanin production by normal and malignant melanocytes. Alpha-2-glycoprotein is produced by both white and brown fat adipocytes and may act in a local autocrine fashion in the reduction of adiposity in cachexia.
Zinc Alpha 2 Glycoprotein/AZGP1 Protein, Human, Recombinant (His)
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$70-In Stock
10 µg$109-In Stock
20 µg$182-In Stock
50 µg$357-In Stock
100 µg$600-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Appearance:Lyophilized powder
Color:White
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Product Information

Bioactivity
Bioactivity
Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Alpha-2-glycoprotein, also known as AZGP1, belongs to the MHC class I family. It can be detected in body fluids such as serum, sweat, and seminal and breast cyst fluids. It has been shown that alpha-2-glycoprotein can stimulate lipolysis by adipocytes in vivo and in vitro. Thus it is believed that alpha-2-glycoprotein plays an important role in the regulation of body weight, and age-dependent changes in genetically influenced obesity, and it also regulates melanin production by normal and malignant melanocytes. Alpha-2-glycoprotein is produced by both white and brown fat adipocytes and may act in a local autocrine fashion in the reduction of adiposity in cachexia.
Species
Human
Expression System
HEK293 Cells
TagC-His
Accession NumberP25311
ConstructionA DNA sequence encoding the human AZGP1 (P25311) (Met1-Ser298) with a C-terminal polyhistidine tag was expressed. Predicted N terminal: Gln 21
Protein Purity
> 95 % as determined by SDS-PAGE
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
ReconstitutionReconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonymsα-2-glycoprotein 1, zinc-binding, Zinc α 2, ZAG, ZA2G, alpha-2-glycoprotein 1, zinc-binding
Research Background
Alpha-2-glycoprotein, also known as AZGP1, belongs to the MHC class I family. It can be detected in body fluids such as serum, sweat, and seminal and breast cyst fluids. It has been shown that alpha-2-glycoprotein can stimulate lipolysis by adipocytes in vivo and in vitro. Thus it is believed that alpha-2-glycoprotein plays an important role in the regulation of body weight, and age-dependent changes in genetically influenced obesity, and it also regulates melanin production by normal and malignant melanocytes. Alpha-2-glycoprotein is produced by both white and brown fat adipocytes and may act in a local autocrine fashion in the reduction of adiposity in cachexia.
Chemical Properties
Molecular Weight33.6 kDa (predicted); 41 kDa (reducing conditions)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: Zinc Alpha 2 Glycoprotein/AZGP1 Protein, Human, Recombinant (His) chemical structure | Zinc Alpha 2 Glycoprotein/AZGP1 Protein, Human, Recombinant (His) molecular weight