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Pomalidomide-PEG4-C2-NH2 hydrochloride

🥰Excellent
Catalog No. T40032Cas No. 2357105-92-9

Pomalidomide-PEG4-C2-NH2 hydrochloride is a PEG-based PROTAC linker used for synthesizing PROTACs[1].

Pomalidomide-PEG4-C2-NH2 hydrochloride
Other Forms of Pomalidomide-PEG4-C2-NH2 hydrochloride:
Pomalidomide-PEG4-C2-NH2T179162225940-52-1
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Pomalidomide-PEG4-C2-NH2 hydrochloride

🥰Excellent
Purity: 98.18%
Catalog No. T40032Cas No. 2357105-92-9
Pomalidomide-PEG4-C2-NH2 hydrochloride is a PEG-based PROTAC linker used for synthesizing PROTACs[1].
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$31In StockIn Stock
25 mg$51In StockIn Stock
50 mgPreferentialIn StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.18%
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COA HPLC HNMR

Product Introduction

Bioactivity
Description
Pomalidomide-PEG4-C2-NH2 hydrochloride is a PEG-based PROTAC linker used for synthesizing PROTACs[1].
In vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein[1].
Chemical Properties
Molecular Weight528.98
FormulaC23H33ClN4O8
Cas No.2357105-92-9
SmilesO=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCOCCOCCOCCN)=O.[H]Cl
Relative Density.no data available
Storage & Solubility Information
StoragePure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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g
μL
2 Enter the in vivo formulation:
% DMSO
%
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% Saline/PBS/ddH2O

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

PROTACLinkerPROTAC LinkerPomalidomide-PEG4-C2-NH2 HydrochloridePomalidomidePEG4C2NH2 hydrochloridePomalidomide PEG4 C2 NH2 hydrochloridePEGsInhibitorinhibitE3 Ligase Ligand-Linker Conjugates
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