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Cyclic-di-GMP

Name: Cyclic-di-GMP
Brand: TargetMol
SKU: T10909
Rating: 4.5 (1 reviews)

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Catalog No. T10909Cas No. 61093-23-0

Alias cyclic diguanylate, c-di-GMP, 5GP-5GP

Cyclic-di-GMP, a STING agonist and ubiquitous second messenger, regulates biofilm formation, motility, and virulence in various bacterial species.

Cyclic-di-GMP

😃Good

Catalog No. T10909Alias cyclic diguanylate, c-di-GMP, 5GP-5GPCas No. 61093-23-0

Cyclic-di-GMP, a STING agonist and ubiquitous second messenger, regulates biofilm formation, motility, and virulence in various bacterial species.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$1,520	6-8 weeks	6-8 weeks
50 mg	$1,980	6-8 weeks	6-8 weeks
100 mg	$2,500	6-8 weeks	6-8 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Product Introduction

Bioactivity

Description	Cyclic-di-GMP, a STING agonist and ubiquitous second messenger, regulates biofilm formation, motility, and virulence in various bacterial species.
Synonyms	cyclic diguanylate, c-di-GMP, 5GP-5GP

Chemical Properties

Molecular Weight	690.41
Formula	C₂₀H₂₄N₁₀O₁₄P₂
Cas No.	61093-23-0
Smiles	O=C1C2=C(N(C=N2)[C@H]3[C@H](O)[C@]4([C@](O3)(COP(=O)(O)O[C@@]5([C@@](COP(=O)(O)O4)(O[C@H]([C@@H]5O)N6C7=C(N=C6)C(=O)N=C(N)N7)[H])[H])[H])[H])NC(N)=N1
Relative Density.	2.70 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 25 mg/mL (36.21 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	1.4484 mL	7.2421 mL	14.4841 mL	72.4207 mL
5 mM	0.2897 mL	1.4484 mL	2.8968 mL	14.4841 mL
10 mM	0.1448 mL	0.7242 mL	1.4484 mL	7.2421 mL
20 mM	0.0724 mL	0.3621 mL	0.7242 mL	3.6210 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline /PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline /PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc