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Anti-Kallikrein 3/KLK3 Antibody (6R985) is a Mouse antibody targeting Kallikrein 3/KLK3. Anti-Kallikrein 3/KLK3 Antibody (6R985) can be used in WB,IHC-P,IHC-Fr,IF,ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $222 | 7-10 days | |
100 μL | $372 | 7-10 days |
Description | Antibody Type: Mouse Monoclonal Application: WB,IHC-P,IHC-Fr,IF,ELISA Reactivity: Human |
Ig Type | IgG |
Clone | 6R985 |
Reactivity | Human |
Verified Activity | Tissue/cell: human prostate carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-PSa (PA5) Polyclonal Antibody, Unconjugated (TMAB-01012) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining. |
Application | WB,IHC-P,IHC-Fr,IF,ELISA |
Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Subcellular Localization | Secreted. |
Construction | Hybridoma Monoclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M PBS (pH7.4) with 0.02% Proclin300. |
Research Background | Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]. |
Immunogen | Full length native protein purified from human |
Antigen Species | Human |
Gene ID | 354 |
Uniprot ID | |
Biology Area | Tumor antigens,Tumor-associated antigens,Proteases,Kallikreins,Tumor Associated |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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