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CEACAM5 Protein, Cynomolgus, Recombinant (aa 35-685, His)
(Synonyms: Meconium antigen 100, DKFZp781M2392, CEACD66e, CEACAM-5, CEA, CD66e, Carcinoembryonic) Copy Product InfoSynonyms: Meconium antigen 100, DKFZp781M2392, CEACD66e, CEACAM-5, CEA, CD66e, Carcinoembryonic
Catalog No. TMPK-01299 Copy Product Info
Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver. CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites. Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors, and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $51 | 7-10 days | 7-10 days | |
| 10 μg | $80 | 7-10 days | 7-10 days | |
| 20 μg | $129 | 7-10 days | 7-10 days | |
| 50 μg | $248 | 7-10 days | 7-10 days | |
| 100 μg | $418 | 7-10 days | 7-10 days | |
| 200 μg | $757 | 7-10 days | 7-10 days | |
| 500 μg | $1,670 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver. CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites. Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors, and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated. |
| Species | Cynomolgus |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | XP_005589491.2 |
| Construction | Gln35-Gly685 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Synonyms | Meconium antigen 100, DKFZp781M2392, CEACD66e, CEACAM-5, CEA, CD66e, Carcinoembryonic |
| Research Background |
| Molecular Weight | 72.76 kDa (predicted). Due to glycosylation, the protein migrates to 120-200 kDa based on Tris-Bis PAGE result. |
| Storage | Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Related Tags: CEACAM5 Protein, Cynomolgus, Recombinant (aa 35-685, His) chemical structure | CEACAM5 Protein, Cynomolgus, Recombinant (aa 35-685, His) molecular weight
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