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Anti-ASGR1 Antibody-HRP (1F863) is a HRP-conjugated Rabbit antibody targeting ASGR1. Anti-ASGR1 Antibody-HRP (1F863) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μg | 390 € | 7-10 days |
Description | Anti-ASGR1 Antibody-HRP (1F863) is a HRP-conjugated Rabbit antibody targeting ASGR1. Anti-ASGR1 Antibody-HRP (1F863) can be used in ELISA. |
Alias | HL-1, CLEC4H1, asialoglycoprotein receptor 1, ASGPR1, ASGPR |
Ig Type | Monoclonal Rabbit IgG |
Clone | 1F863 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 0.1-1 μg/ml |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human ASGPR1 (rh ASGPR1 ; TMPY-02702; P07306; Gln62-Leu291), and conjugated with horseradish-peroxidase (HRP). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | The asialoglycoprotein receptor (ASGPR), an endocytotic cell surface receptor expressed by hepatocytes, is triggered by triantennary binding to galactose residues of macromolecules such as asialoorosomucoid (ASOR). ASGPR belongs to the long-form subfamily of the C-type/Ca2+ dependent lectin family. It is a complex of two noncovalently-linked and highly homologous subunits, a major 42 kDa glycoprotein ASGPR1(MHL-1) and a minor 51 kDa glycoprotein ASGR2 (MHL-2). ASGPR1 is synthesized as a type II transmembrane protein that contains a cytosolic N-terminal domain, a single transmembrane segment, and an extracellular domain which contains two important structural regions. The first is a stalk domain that contributes to noncovalent oligomerization, and the second is a Ca2+-dependent carbohydrate binding domain at the very C-terminus that is unusually stabilized by three ions. The research regarded that ASGPR1 could be targeted for anti- hepatitis B virus (HBV) drug development. |
Conjucates | HRP |
Others Formats | Unconjugated |
Antibody Types Available | 2 |
Immunogen | Recombinant Human ASGPR1 Protein (TMPY-02702) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight. |
Transport | Shipping with blue ice. |
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