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LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc)
(Synonyms: LIR-7, LIR7, leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2, ILT1, CD85H) Copy Product InfoSynonyms: LIR-7, LIR7, leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2, ILT1, CD85H
Catalog No. TMPY-06076 Copy Product Info
Purity: 98%
LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.7 kDa and the accession number is Q8N149-1.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $55 | - | In Stock | |
| 10 µg | $86 | - | In Stock | |
| 20 µg | $139 | - | In Stock | |
| 50 µg | $269 | - | In Stock | |
| 100 µg | $451 | - | In Stock | |
| 200 µg | $798 | 7-10 days | 7-10 days | |
| 500 µg | $1,690 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:98%
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.7 kDa and the accession number is Q8N149-1. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-hFc |
| Accession Number | Q8N149-1 |
| Construction | A DNA sequence encoding the human LILRA2 (NP_001124389.2) (Met1-Asn449) was expressed with the Fc region of human IgG1 at the C-terminus. Predicted N terminal: Gly 24 |
| Protein Purity | > 95 % as determined by SDS-PAGE.  |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
| Reconstitution | Reconstituted with PBS, pH 7.4 to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot. |
| Synonyms | LIR-7, LIR7, leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2, ILT1, CD85H |
| Research Background | LILRA2 (Leukocyte Immunoglobulin Like Receptor A2, also known as LIR7 and ILT1) is a Protein Coding gene. The encoded protein is an activating receptor that inhibits dendritic cell differentiation and antigen presentation and suppresses the innate immune response. It is an activating receptor highly expressed in inflammatory tissues and is involved in granulocyte and macrophage activation. LILRA2 is primarily expressed on the surface of cells of the innate immunity including monocytes, macrophages, neutrophils, basophils, and eosinophils but not on lymphocytes and NK cells. LILRA2 cross-linking on monocytes induces pro-inflammatory cytokines while inhibiting dendritic cell differentiation and antigen presentation. Diseases associated with LILRA2 include Tuberculoid Leprosy and Leprosy 3. |
| Molecular Weight | 73.7 kDa (predicted); 92.7 kDa (reducing condition, due to glycosylation) |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc) chemical structure | LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc) molecular weight
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