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Anti-ITGAX Antibody (4P951) (Synonyms: SLEB6, leukocyte adhesion receptor p150, 95, leukocyte adhesion glycopr...)

Catalog No. TMAC-00651 Copy Product Info
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Anti-ITGAX Antibody (4P951) is a Rabbit antibody targeting ITGAX. Anti-ITGAX Antibody (4P951) can be used in IHC,IP,ICC/IF,WB.

Anti-ITGAX Antibody (4P951)

Copy Product Info
🥰Excellent
Catalog No. TMAC-00651
Synonyms SLEB6, leukocyte adhesion receptor p150, 95, leukocyte adhesion glycoprotein p150, 95 alpha chain, ITGAX, ITAX, integrin aX, integrin alpha-X precursor, Integrin alpha-X, complement receptor 4, CD11C(p150) alpha polypeptide, CD11 antigen-like family member C

Anti-ITGAX Antibody (4P951) is a Rabbit antibody targeting ITGAX. Anti-ITGAX Antibody (4P951) can be used in IHC,IP,ICC/IF,WB.

Anti-ITGAX Antibody
(4P951)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ITGAX Antibody (4P951) is a Rabbit antibody targeting ITGAX. Anti-ITGAX Antibody (4P951) can be used in IHC,IP,ICC/IF,WB.
SynonymsSLEB6, leukocyte adhesion receptor p150, 95, leukocyte adhesion glycoprotein p150, 95 alpha chain, ITGAX, ITAX, integrin aX, integrin alpha-X precursor, Integrin alpha-X, complement receptor 4, CD11C(p150) alpha polypeptide, CD11 antigen-like family member C
Ig Type
IgG
Clone
4P951
Reactivity
Human
Verified Activity
1. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-CD11c antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-CD11c antibody. Counter stained with hematoxylin.
verifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundIntegrin αX (CD11C, leukocyte surface antigen p150,95, CR4, Axb2) is a type 1 transmembrane protein that traditionally combines with β2 chain to form a leukocyte-specific integrin known as inactivated-C3b (iC3b) receptor 4 (CR4). Integrin αX/β2 shares similar properties of the αM/β2 integrin in mediating adherence of neutrophils and monocytes to stimulated endothelial cells, and in phagocytosis of complement coated particles. Abnormal expression of Integrin αX is characteristic of hairy cell leukemia (HCL) and is dependent upon activation of proto-oncogenes Ras and JunD. Proteins and DNA elements that influence transcription of Integrin αX include Sp1 and Sp1-like factors, AP-1 family, C/EBP, Oct-2 and PU.1. Integrin αX is present on monocyte derivative dendritic cells (DCs), macrophages and NK cells. Upon activation, DCs present in skin (Langerhans cells), lining of nose, lung, stomach, intestine and blood can migrate to lymphoid tissues and interact with T and B cells to initiate and shape the immune response.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 128 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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