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Anti-Renin Antibody (3M934)

😃Good
Catalog No. TMAY-01383
Alias renin, REN, HNFJ2, FLJ10761

Anti-Renin Antibody (3M934) is a Mouse antibody targeting Renin. Anti-Renin Antibody (3M934) can be used in IHC-P.

Anti-Renin Antibody (3M934)

Anti-Renin Antibody (3M934)

😃Good
Catalog No. TMAY-01383Alias renin, REN, HNFJ2, FLJ10761
Anti-Renin Antibody (3M934) is a Mouse antibody targeting Renin. Anti-Renin Antibody (3M934) can be used in IHC-P.
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100 μL$198 7-10 days
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Product Introduction

Bioactivity
Description
Anti-Renin Antibody (3M934) is a Mouse antibody targeting Renin. Anti-Renin Antibody (3M934) can be used in IHC-P.
Aliasrenin, REN, HNFJ2, FLJ10761
Ig Type
Monoclonal Mouse IgG1
Clone
3M934
Reactivity
Human
Verified Activity
Immunochemical staining of human RENIN in human kidney (from 2 donors) with mouse monoclonal antibody (1:60, formalin-fixed paraffin embedded sections).
Application
IHC-P
Recommended Dose
IHC-P: 1:50-1:200
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Renin / REN (rh Renin / REN; TMPY-00908; NP_000528.1; Met1-Arg406). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundRenin-1, also known as Ren-1, Angiotensinogenase and Kidney renin, is a member of the peptidase A1 family. Renin-1 is synthesized by the juxtaglomerular cells of the kidney in response to decreased blood pressure and sodium concentration. androgen and thyroid hormones influence levels of Renin-1 in mouse submandibular gland (SMG) primarily by regulating the amount of Renin-1 mRNA available for translation. Renin-1 is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney. It is expressed at relatively low levels in mouse SMG and kidney. Ren-2 is expressed at high levels in the mouse SMG and at very low levels, if at all, in the kidney. Ren-1 and Ren-2 are closely linked on mouse chromosome 1, show extensive homology in coding and noncoding regions and provide a model for studying the regulation of gene expression.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human Renin / REN protein (TMPY-00908)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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