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Synonyms: Small-inducible cytokine B10, Scyb10, Interferon-gamma induced protein CRG-2, Inp10, Ifi10, Cxcl10, C-X-C motif chemokine 10, Crg2, C7, 10 kDa interferon gamma-induced protein (Gamma-IP10;IP-10)

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $198 | - | In Stock | |
| 10 µg | $296 | 7-10 days | 7-10 days | |
| 20 µg | $472 | 7-10 days | 7-10 days | |
| 50 µg | $858 | 7-10 days | 7-10 days | |
| 100 µg | $1,330 | 7-10 days | 7-10 days | |
| 200 µg | $1,890 | 7-10 days | 7-10 days | |
| 500 µg | $2,960 | 7-10 days | 7-10 days |
| Bioactivity | Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human peripheral blood lymphocytes is in a concentration range of 0.1- 10.0 ng/mL in the presence of IL-2. |
| Description | CXCL10 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.7 kDa and the accession number is P17515. |
| Species | Mouse |
| Expression System | E. coli |
| Tag | Tag Free |
| Accession Number | P17515 |
| Amino Acid | IPLARTVRCN CIHIDDGPVR MRAIGKLEII PASLSCPRVE IIATMKKNDE QRCLNPESKT IKNLMKAFSQ KRSKRAP |
| Construction | 22-98 aa |
| Protein Purity | >97% as determined by SDS-PAGE. ![]() |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | 0.2 μm filtered 2×PBS, pH 7.4, lyophilized. |
| Reconstitution | A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information. |
| Synonyms | Small-inducible cytokine B10, Scyb10, Interferon-gamma induced protein CRG-2, Inp10, Ifi10, Cxcl10, C-X-C motif chemokine 10, Crg2, C7, 10 kDa interferon gamma-induced protein (Gamma-IP10;IP-10) |
| Research Background | (C-X-C motif) ligand (CXCL)10 (CXCL10) belongs to the ELR(-) CXC subfamily chemokine. CXCL10/IP-10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3), a seven trans-membrane receptor coupled to G proteins. CXCL10/IP-10 and its receptor, CXCR3, appear to contribute to the pathogenesis of many autoimmune diseases, organ specific (such as type 1 diabetes, autoimmune thyroiditis, Graves' disease and ophthalmopathy), or systemic (such as rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus, mixed cryoglobulinemia, Sjögren syndrome, or systemic sclerosis). CXCL10/IP-10 is secreted by several cell types including endothelial cells, fibroblasts, keratinocytes, thyrocytes, preadipocytes, etc. Determination of high level of CXCL10/IP-10 in peripheral fluids is therefore a marker of host immune response. |
| Molecular Weight | 8.7 kDa as predicted |
| Relative Density. | no data available |
| Shipping | In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice. |
| Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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