Shopping Cart

Remove All
Your shopping cart is currently empty

PHA 568487 free base

Name: PHA 568487 free base
Brand: TargetMol
SKU: T23146
Price: 37 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T23146Cas No. 527680-56-4

Alias PHA 568487

The quinuclidine PHA 568487 free base is an agonist of the alpha 7 nicotinic acetylcholine receptor that was designed to mitigate the bioactivation associated with the core scaffold and subsequently remove associated liabilities with in vivo tolerability.

PHA 568487 free base

🥰Excellent

Purity: 99.74%

Catalog No. T23146Alias PHA 568487Cas No. 527680-56-4

Pack Size	Price	Availability
10 mg	$37	In Stock
25 mg	$68	In Stock
50 mg	$132	In Stock
100 mg	$237	In Stock
200 mg	$331	In Stock

Add to Cart

Add to Quotation

Bulk & Custom

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.74%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	The quinuclidine PHA 568487 free base is an agonist of the alpha 7 nicotinic acetylcholine receptor that was designed to mitigate the bioactivation associated with the core scaffold and subsequently remove associated liabilities with in vivo tolerability.
Synonyms	PHA 568487

Chemical Properties

Molecular Weight	288.34
Formula	C₁₆H₂₀N₂O₃
Cas No.	527680-56-4
Smiles	O=C(N[C@H]1CN2CCC1CC2)c1ccc2OCCOc2c1
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 30 mg/mL (104.04 mM), Sonication is recommended.

H2O: < 40.44 mg/mL (100 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	3.4681 mL	17.3406 mL	34.6813 mL	173.4064 mL
5 mM	0.6936 mL	3.4681 mL	6.9363 mL	34.6813 mL
10 mM	0.3468 mL	1.7341 mL	3.4681 mL	17.3406 mL
20 mM	0.1734 mL	0.8670 mL	1.7341 mL	8.6703 mL
50 mM	0.0694 mL	0.3468 mL	0.6936 mL	3.4681 mL
100 mM	0.0347 mL	0.1734 mL	0.3468 mL	1.7341 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc