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Pinacidil

Name: Pinacidil
Brand: TargetMol
SKU: T12478L
Price: 42 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T12478LCas No. 60560-33-0

Alias S-1230, S 1230, P-1134, P1134, P 1134

Pinacidil (P 1134) is a guanidine that opens potassium channels and directly dilates peripheral blood vessels in small arteries, lowering blood pressure and peripheral resistance and producing fluid retention.

Pinacidil

🥰Excellent

Purity: 99.9%

Catalog No. T12478LAlias S-1230, S 1230, P-1134, P1134, P 1134Cas No. 60560-33-0

Pack Size	Price	Availability
5 mg	$42	In Stock
10 mg	$58	In Stock
25 mg	$97	In Stock
50 mg	$165	In Stock
1 mL x 10 mM (in DMSO)	$46	In Stock

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Batch Information

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Purity:99.9%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Pinacidil (P 1134) is a guanidine that opens potassium channels and directly dilates peripheral blood vessels in small arteries, lowering blood pressure and peripheral resistance and producing fluid retention.
Synonyms	S-1230, S 1230, P-1134, P1134, P 1134

Chemical Properties

Molecular Weight	245.32
Formula	C₁₃H₁₉N₅
Cas No.	60560-33-0
Smiles	CC(N\C(Nc1ccncc1)=N/C#N)C(C)(C)C
Relative Density.	1.1402 g/cm3 (Estimated)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (407.63 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.0763 mL	20.3815 mL	40.7631 mL	203.8154 mL
5 mM	0.8153 mL	4.0763 mL	8.1526 mL	40.7631 mL
10 mM	0.4076 mL	2.0382 mL	4.0763 mL	20.3815 mL
20 mM	0.2038 mL	1.0191 mL	2.0382 mL	10.1908 mL
50 mM	0.0815 mL	0.4076 mL	0.8153 mL	4.0763 mL
100 mM	0.0408 mL	0.2038 mL	0.4076 mL	2.0382 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc