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Anti-Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G Antibody (5J298)
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Catalog No. TMAY-01591
Anti-Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G Antibody (5J298) is a Mouse antibody targeting Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G. Anti-Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G Antibody (5J298) can be used in WB,ELISA.
Anti-Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G Antibody (5J298)
Anti-Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G Antibody (5J298)
😃Good
Catalog No. TMAY-01591
Anti-Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G Antibody (5J298) is a Mouse antibody targeting Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G. Anti-Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G Antibody (5J298) can be used in WB,ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $92 | 7-10 days | |
| 100 μL | $294 | 7-10 days |
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Chemical Properties
| Description | Anti-Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G Antibody (5J298) is a Mouse antibody targeting Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G. Anti-Human respiratory syncytial virus (RSV) Glycoprotein G/RSV-G Antibody (5J298) can be used in WB,ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 5J298 |
| Application | WB,ELISA |
| Recommended Dose | WB: 1:500-1:1000; ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human RSV Glycoprotein G/RSV-G (HRSV-G; Asn66-Arg297P27022-1). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. It is classified within the genus pneumovirus of the family paramyxoviridae. Like other members of the family, HRSV has two major surface glycoproteins (G and F) that play important roles in the initial stages of the infectious cycle. HRSV G protein is a type II glycoprotein of 289-299 amino acids (depending on the virus strain) with a signal/anchor hydrophobic domain and is extensively modified by the addition of both N-and O-linked oligosaccharides to achieve the mature form of 8-9 kDa. The C-terminal ectodomain of the G protein has a central region and four cysteines which are conserved in all HRSV isolates and have been proposed as the putative receptor binding site. The G protein mediates attachment of the virus to the host cell membrane by interacting with heparan sulfate, initiating the infection. As similar to mucins in amino acid compositions, the RSV G protein can interact with host CX3CR1, the receptor for the CX3C chemokine fractalkine, and thus modulates the immune response and facilitate infection. Secreted glycoprotein G helps RSV escape antibody-dependent restriction of replication by acting as an antigen decoy and by modulating the activity of leukocytes bearing Fcgamma receptors. Unlike the other paramyxovirus attachment proteins, HRSV-G lacks both neuraminidase and hemagglutinating activities. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human RSV Glycoprotein G / RSV-G |
| Antigen Species | RSV |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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