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Primidone

Name: Primidone
Brand: TargetMol
SKU: T0024
Price: 33 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T0024Cas No. 125-33-7

Alias Primaclone, NCI-C56360, Mysoline

Primidone (NCI-C56360) is a potent anticonvulsant agent. It is a neuronal voltage-gated sodium channel blocker and has value in the study of epilepsy, essential tremor, and psychiatric disorders.

Primidone

🥰Excellent

Purity: 99.91%

Catalog No. T0024Alias Primaclone, NCI-C56360, MysolineCas No. 125-33-7

Primidone (NCI-C56360) is a potent anticonvulsant agent. It is a neuronal voltage-gated sodium channel blocker and has value in the study of epilepsy, essential tremor, and psychiatric disorders.

Pack Size	Price	Availability
100 mg	$33	In Stock
500 mg	$74	In Stock
1 g	$108	In Stock

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Batch Information

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Purity:99.91%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Primidone (NCI-C56360) is a potent anticonvulsant agent. It is a neuronal voltage-gated sodium channel blocker and has value in the study of epilepsy, essential tremor, and psychiatric disorders.
Synonyms	Primaclone, NCI-C56360, Mysoline

Chemical Properties

Molecular Weight	218.25
Formula	C₁₂H₁₄N₂O₂
Cas No.	125-33-7
Smiles	CCC1(C(=O)NCNC1=O)C1=CC=CC=C1
Relative Density.	1.138g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 70 mg/mL (320.73 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (9.16 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.5819 mL	22.9095 mL	45.8190 mL	229.0951 mL
5 mM	0.9164 mL	4.5819 mL	9.1638 mL	45.8190 mL
10 mM	0.4582 mL	2.2910 mL	4.5819 mL	22.9095 mL
20 mM	0.2291 mL	1.1455 mL	2.2910 mL	11.4548 mL
50 mM	0.0916 mL	0.4582 mL	0.9164 mL	4.5819 mL
100 mM	0.0458 mL	0.2291 mL	0.4582 mL	2.2910 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc