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Anti-PD-1 Antibody (6A192) (Synonyms: SLEB2, programmed cell death 1, PD-1, PD1, hSLE1, hPD-l, hPD-1, CD2...)

Catalog No. TMAC-03106 Copy Product Info
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Anti-PD-1 Antibody (6A192) is a Rabbit antibody targeting PD-1. Anti-PD-1 Antibody (6A192) can be used in IHC,WB.

Anti-PD-1 Antibody (6A192)

Copy Product Info
🥰Excellent
Catalog No. TMAC-03106
Synonyms SLEB2, programmed cell death 1, PD-1, PD1, hSLE1, hPD-l, hPD-1, CD279

Anti-PD-1 Antibody (6A192) is a Rabbit antibody targeting PD-1. Anti-PD-1 Antibody (6A192) can be used in IHC,WB.

Anti-PD-1 Antibody
(6A192)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4977-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-PD-1 Antibody (6A192) is a Rabbit antibody targeting PD-1. Anti-PD-1 Antibody (6A192) can be used in IHC,WB.
SynonymsSLEB2, programmed cell death 1, PD-1, PD1, hSLE1, hPD-l, hPD-1, CD279
Ig Type
IgG
Clone
6A192
Reactivity
Human
Verified Activity
1. Western blot analysis of over-expressed PD1 (whole extracellular domain) on 293T cell lysate using anti-PD1 antibody at 1/500 dilution.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-PD1 antibody. Counter stained with hematoxylin.
verifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundPdcd-1 (Programmed Cell Death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. Pdcd-1 contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) within the cytoplasmic domain, which is conserved between the mouse and human homologs. Expression of Pdcd-1 is detected in mouse thymus, and it is induced in stimulated B and T cell lines, where it may play a role in the negative regulation of various immune responses. Receptors such as Pdcd-1 function by recruiting tyrosine phosphatases, including SHP-1 and SHIP, which are responsible for altering various B cell responses. Additionally, in activated lymphocytes, Pdcd-1 mediates the activation of the classical type of programmed cell death.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 32 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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