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Anti-PD-1 Antibody (6A192)

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Catalog No. TMAC-03106
Alias SLEB2, programmed cell death 1, PD-1, PD1, hSLE1, hPD-l, hPD-1, CD279

Anti-PD-1 Antibody (6A192) is a Rabbit antibody targeting PD-1. Anti-PD-1 Antibody (6A192) can be used in WB,IHC.

Anti-PD-1 Antibody (6A192)

Anti-PD-1 Antibody (6A192)

😃Good
Catalog No. TMAC-03106Alias SLEB2, programmed cell death 1, PD-1, PD1, hSLE1, hPD-l, hPD-1, CD279
Anti-PD-1 Antibody (6A192) is a Rabbit antibody targeting PD-1. Anti-PD-1 Antibody (6A192) can be used in WB,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-PD-1 Antibody (6A192) is a Rabbit antibody targeting PD-1. Anti-PD-1 Antibody (6A192) can be used in WB,IHC.
SynonymsSLEB2, programmed cell death 1, PD-1, PD1, hSLE1, hPD-l, hPD-1, CD279
Ig Type
IgG
Reactivity
Human
Verified Activity
1. Western blot analysis of over-expressed PD1 (whole extracellular domain) on 293T cell lysate using anti-PD1 antibody at 1/500 dilution.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-PD1 antibody. Counter stained with hematoxylin.
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundPdcd-1 (Programmed Cell Death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. Pdcd-1 contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) within the cytoplasmic domain, which is conserved between the mouse and human homologs. Expression of Pdcd-1 is detected in mouse thymus, and it is induced in stimulated B and T cell lines, where it may play a role in the negative regulation of various immune responses. Receptors such as Pdcd-1 function by recruiting tyrosine phosphatases, including SHP-1 and SHIP, which are responsible for altering various B cell responses. Additionally, in activated lymphocytes, Pdcd-1 mediates the activation of the classical type of programmed cell death.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 32 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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