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Zidebactam

Name: Zidebactam
Brand: TargetMol
SKU: T13395L
Price: 88 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T13395LCas No. 1436861-97-0

Alias WCK-5107

Zidebactam (WCK-5107) is an effective β-lactamase inhibitor. Zidebactam also is a penicillin-binding protein2 inhibitor (IC50: 0.26 μg/mL).

Zidebactam

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Purity: 99.69%

Catalog No. T13395LAlias WCK-5107Cas No. 1436861-97-0

Zidebactam (WCK-5107) is an effective β-lactamase inhibitor. Zidebactam also is a penicillin-binding protein2 inhibitor (IC50: 0.26 μg/mL).

Pack Size	Price	Availability
1 mg	$88	In Stock
5 mg	$189	In Stock
10 mg	$313	In Stock
25 mg	$533	In Stock
50 mg	$768	In Stock
100 mg	$1,080	In Stock

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Purity:99.69%

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COA HPLC HNMR

Product Introduction

Bioactivity

Description	Zidebactam (WCK-5107) is an effective β-lactamase inhibitor. Zidebactam also is a penicillin-binding protein2 inhibitor (IC50: 0.26 μg/mL).
Targets&IC50	E. coli:0.12 mg/L (MIC50), PBP2:0.26 μg/ml (P. aeruginosa PAO1 PBP2), Enterobacter spp:0.12 mg/L (MIC50), Enterobacteriaceae (WT):0.25 mg/L (MIC50)
In vitro	Zidebactam inhibits WT Enterobacteriaceae (MIC50: 0.25?mg/L). Zidebactam alone shows variable activity when tested against E. coli (MIC50/90 0.12/0.12? mg/L) and Enterobacter spp. (MIC50/90 0.12/0.25? mg/L) [1].
Synonyms	WCK-5107

Chemical Properties

Molecular Weight	391.4
Formula	C₁₃H₂₁N₅O₇S
Cas No.	1436861-97-0
Smiles	OS(=O)(=O)ON1[C@H]2CN([C@@H](CC2)C(=O)NNC(=O)[C@@H]2CCCNC2)C1=O
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (638.73 mM), Sonication is recommended.

H2O: 50 mg/mL (127.75 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.5549 mL	12.7747 mL	25.5493 mL	127.7466 mL
5 mM	0.5110 mL	2.5549 mL	5.1099 mL	25.5493 mL
10 mM	0.2555 mL	1.2775 mL	2.5549 mL	12.7747 mL
20 mM	0.1277 mL	0.6387 mL	1.2775 mL	6.3873 mL
50 mM	0.0511 mL	0.2555 mL	0.5110 mL	2.5549 mL
100 mM	0.0255 mL	0.1277 mL	0.2555 mL	1.2775 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc