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Anti-Aminopeptidase N/CD13 Antibody (3R860)

😃Good
Catalog No. TMAY-00183
Alias P150, Cd13, AP-N, Apn, AP-M, alanyl (membrane) aminopeptidase

Anti-Aminopeptidase N/CD13 Antibody (3R860) is a Rabbit antibody targeting Aminopeptidase N/CD13. Anti-Aminopeptidase N/CD13 Antibody (3R860) can be used in ICC/IF.

Anti-Aminopeptidase N/CD13 Antibody (3R860)

Anti-Aminopeptidase N/CD13 Antibody (3R860)

😃Good
Catalog No. TMAY-00183Alias P150, Cd13, AP-N, Apn, AP-M, alanyl (membrane) aminopeptidase
Anti-Aminopeptidase N/CD13 Antibody (3R860) is a Rabbit antibody targeting Aminopeptidase N/CD13. Anti-Aminopeptidase N/CD13 Antibody (3R860) can be used in ICC/IF.
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100 μL$268 7-10 days
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Product Introduction

Bioactivity
Description
Anti-Aminopeptidase N/CD13 Antibody (3R860) is a Rabbit antibody targeting Aminopeptidase N/CD13. Anti-Aminopeptidase N/CD13 Antibody (3R860) can be used in ICC/IF.
AliasP150, Cd13, AP-N, Apn, AP-M, alanyl (membrane) aminopeptidase
Ig Type
Monoclonal Rabbit IgG
Clone
3R860
Reactivity
Human
Verified Activity
Immunofluorescence staining of Human CD13 in MSC cells. Cells were fixed with 4% PFA, permeabilzed with 0.3% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human CD13 monoclonal antibody (1:60) at 4°C overnight. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue).
Application
ICC/IF
Recommended Dose
ICC-IF: 1:20-1:100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human CD13 / ANPEP (rh CD13 / ANPEP; TMPY-00665; NP_001141.2; Lys69-Lys967,603Met/Ile).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundAminopeptidase N (ANPEP or APN), also known as CD13, is a cell-surface metalloprotease located in the small-intestinal and renal microvillar membrane, as well as other plasma membranes. It belongs to the peptidase M1 family. CD13 plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases and is involved in the metabolism of regulatory peptides by diverse cell types. CD13/APN is a potent regulator of angiogenesis which is essential for tumor invasion and metastasis, and its transcription in activated endothelial cells is induced by angiogenic growth factors via the RAS/MAPK pathway. In addition, this enzyme has been shown to participate in antigen processing and presentation, and accordingly, defects in this gene appear to be a cause of various types of leukemia or lymphoma and carcinomas.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human CD13 / ANPEP Protein (TMPY-00665)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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