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Anti-Phospho-LATS1/2 (Thr1079/1041) Polyclonal Antibody 2
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Catalog No. TMAC-02375
Alias p-LATS1/2 (Thr1079/1041), p-LATS1/2 (T1079/1041), LATS1/2 (p-Thr1079/1041), LATS1/2 (p-T1079/1041)
Anti-Phospho-LATS1/2 (Thr1079/1041) Polyclonal Antibody is a Rabbit antibody targeting Phospho-LATS1/2 (Thr1079/1041). Anti-Phospho-LATS1/2 (Thr1079/1041) Polyclonal Antibody can be used in IHC.
Anti-Phospho-LATS1/2 (Thr1079/1041) Polyclonal Antibody 2
Anti-Phospho-LATS1/2 (Thr1079/1041) Polyclonal Antibody 2
😃Good
Catalog No. TMAC-02375Alias p-LATS1/2 (Thr1079/1041), p-LATS1/2 (T1079/1041), LATS1/2 (p-Thr1079/1041), LATS1/2 (p-T1079/1041)
Anti-Phospho-LATS1/2 (Thr1079/1041) Polyclonal Antibody is a Rabbit antibody targeting Phospho-LATS1/2 (Thr1079/1041). Anti-Phospho-LATS1/2 (Thr1079/1041) Polyclonal Antibody can be used in IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $218 | 7-10 days | |
| 100 μL | $317 | 7-10 days |
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Product Introduction
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Antigen Details
Chemical Properties
| Description | Anti-Phospho-LATS1/2 (Thr1079/1041) Polyclonal Antibody is a Rabbit antibody targeting Phospho-LATS1/2 (Thr1079/1041). Anti-Phospho-LATS1/2 (Thr1079/1041) Polyclonal Antibody can be used in IHC. |
| Synonyms | p-LATS1/2 (Thr1079/1041), p-LATS1/2 (T1079/1041), LATS1/2 (p-Thr1079/1041), LATS1/2 (p-T1079/1041) |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded human brain tissue using LATS1/2 (Phospho-Thr1079/1041) antibody TMAC-02375 (left) or the same antibody preincubated with blocking peptide (right). |
| Application | |
| Recommended Dose | IHC: 1:50-100 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell-cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative regulator of CDC2/cyclin A. In addition, the C-terminal kinase domain binds to its own N-terminal region, suggesting potential negative regulation through interference with complex formation via intramolecular binding. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of threonine 1079/1041 (E-F-T(p)-F-R) derived from Human LATS1/2 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 126 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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