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Synonyms: Zinc finger FYVE domain-containing protein 2, ZFYVE2, MSTP105, MST105, Endosome-associated protein p162, EEA1, EEA 1, Early endosome associated protein, Early endosome antigen 1, 162kD, Early endosome antigen 1
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
| Description | Anti-EEA1 Polyclonal Antibody is a Rabbit antibody targeting EEA1. Anti-EEA1 Polyclonal Antibody can be used in FCM, IF, IHC-Fr, IHC-P. |
| Synonyms | Zinc finger FYVE domain-containing protein 2, ZFYVE2, MSTP105, MST105, Endosome-associated protein p162, EEA1, EEA 1, Early endosome associated protein, Early endosome antigen 1, 162kD, Early endosome antigen 1 |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Dog,Cow,Hamster) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1ug/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Early endosome membrane. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Early endosomes are cytoplasmic compartments that function in receiving and sorting endocytosed proteins for vesicular transport. EEA1 (early endosome antigen 1) is a peripheral membrane protein that co-localizes with the transferrin receptor and Rab5 on early endosomes. EEA1 contains a calmodulin-binding IQ motif and cysteine rich finger motif necessary for its specific localization to the early endosomes. EEA1 has sequence homology to several yeast proteins that have been implicated in membrane trafficking, including Vps27, Fab1 and Vac1. Evidence suggests a possible role for EEA1 in mediating the regulatory effects of 3'-phosphoinositides on membrane trafficking. |
| Immunogen | KLH conjugated synthetic peptide: human EEA1 |
| Antigen Species | Human |
| Gene Name | EEA1 |
| Gene ID | |
| Protein Name | Early endosome antigen 1 |
| Uniprot ID | |
| Biology Area | Soma marker,Regulation,Organelle Proteins,Endosome |
| Function | Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking. |
| Molecular Weight | Theoretical: 162 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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