IL-5 Protein, Human, Recombinant (HEK293)

Name: IL-5 Protein, Human, Recombinant (HEK293)
Brand: TargetMol
SKU: TMPY-07129
Rating: 4.5 (1 reviews)

(Synonyms: TRF, IL-5, EDF) Copy Product Info

Synonyms: TRF, IL-5, EDF

Catalog No. TMPY-07129 Copy Product Info

IL-5 Protein, Human, Recombinant (HEK293) is expressed in HEK293 Cells. The accession number is P05113-1.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$98	7-10 days	7-10 days
10 µg	$167	7-10 days	7-10 days
20 µg	$275	7-10 days	7-10 days
50 µg	$463	7-10 days	7-10 days
100 µg	$790	7-10 days	7-10 days
200 µg	$1,150	7-10 days	7-10 days
500 µg	$2,330	7-10 days	7-10 days
1 mg	$4,550	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	1. Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 0.1-1 ng/mL. 2. Loaded IL-5R alpha/CD125 Protein, Human, Recombinant (Membrane-bound, His) (Cat#TMPY-07016) on HIS1K Biosensor, can bind IL-5 Protein, Human, Recombinant (HEK293) (Cat#TMPY-07129) with an affinity constant of 43.200 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested).
Description	IL-5 Protein, Human, Recombinant (HEK293) is expressed in HEK293 Cells. The accession number is P05113-1.
Species	Human
Expression System	HEK293 Cells
Tag	Tag Free
Accession Number	P05113-1
Construction	A DNA sequence encoding the human IL5 (NP_000870.1) (Ile20-Ser134) was expressed.
Protein Purity	> 95% as determined by SDS-PAGE.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Please refer to the lot-specific COA.
Synonyms	TRF, IL-5, EDF
Research Background	Interleukin 5 (IL-5) is a member of the interleukin family with a length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blood cells (leukocytes) and has been found in a wide variety of body cells. Interleukin 5 or IL-5 is produced by T helper-2 cells and mast cells. It helps to stimulate B cell growth and increase immunoglobulin secretion and is considered a key mediator in eosinophil activation. Interleukin 5 (IL-5) has long been associated with several allergic diseases, including allergic rhinitis and asthma. Growth in the number of circulating, airway tissue, and induced sputum eosinophils have been observed in patients with these diseases. IL-5 also had something with the terminally differentiated granulocyte eosinophils. IL-5 was originally found as an eosinophil colony-stimulating factor. It has been proved to be a major regulator of eosinophil accumulation in tissues and can modulate eosinophil behavior at every stage from maturation to survival.

Chemical Properties

Molecular Weight

13.15 kDa (predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.