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Tiotropium bromide

Name: Tiotropium bromide
Brand: TargetMol
SKU: T1179
Price: 45 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T1179Cas No. 136310-93-5

Alias Tiopropium, BA679 BR

Tiotropium bromide (BA679 BR) is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). Tiotropium is a muscarinic receptor antagonist, on topical application it acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation, thus producing a bronchodilatory effect.

Tiotropium bromide

🥰Excellent

Purity: 99.97%

Catalog No. T1179Alias Tiopropium, BA679 BRCas No. 136310-93-5

Pack Size	Price	Availability
10 mg	$45	In Stock
25 mg	$61	In Stock
50 mg	$77	In Stock
100 mg	$109	In Stock
500 mg	$369	In Stock
1 mL x 10 mM (in DMSO)	$48	In Stock

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Batch Information

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Purity:99.97%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Tiotropium bromide (BA679 BR) is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). Tiotropium is a muscarinic receptor antagonist, on topical application it acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation, thus producing a bronchodilatory effect.
Synonyms	Tiopropium, BA679 BR

Chemical Properties

Molecular Weight	472.42
Formula	C₁₉H₂₂BrNO₄S₂
Cas No.	136310-93-5
Smiles	[Br-].C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)C(O)(c1cccs1)c1cccs1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (116.42 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1168 mL	10.5838 mL	21.1676 mL	105.8380 mL
5 mM	0.4234 mL	2.1168 mL	4.2335 mL	21.1676 mL
10 mM	0.2117 mL	1.0584 mL	2.1168 mL	10.5838 mL
20 mM	0.1058 mL	0.5292 mL	1.0584 mL	5.2919 mL
50 mM	0.0423 mL	0.2117 mL	0.4234 mL	2.1168 mL
100 mM	0.0212 mL	0.1058 mL	0.2117 mL	1.0584 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc