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Tiotropium bromide

🥰Excellent
Catalog No. T1179Cas No. 136310-93-5
Alias Tiopropium, BA679 BR

Tiotropium bromide (BA679 BR) is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). Tiotropium is a muscarinic receptor antagonist, on topical application it acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation, thus producing a bronchodilatory effect.

Tiotropium bromide
Other Forms of Tiotropium bromide:
Tiotropium Bromide hydrateT6707411207-31-3
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Tiotropium bromide

🥰Excellent
Purity: 99.97%
Catalog No. T1179Alias Tiopropium, BA679 BRCas No. 136310-93-5
Tiotropium bromide (BA679 BR) is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). Tiotropium is a muscarinic receptor antagonist, on topical application it acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation, thus producing a bronchodilatory effect.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$45In StockIn Stock
25 mg$61In StockIn Stock
50 mg$77In StockIn Stock
100 mg$109In StockIn Stock
500 mg$369-In Stock
1 mL x 10 mM (in DMSO)$48In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.97%
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COA LCMS HNMR

Product Introduction

Bioactivity
Description
Tiotropium bromide (BA679 BR) is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). Tiotropium is a muscarinic receptor antagonist, on topical application it acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation, thus producing a bronchodilatory effect.
SynonymsTiopropium, BA679 BR
Chemical Properties
Molecular Weight472.42
FormulaC19H22BrNO4S2
Cas No.136310-93-5
Smiles[Br-].C[N+]1(C)[C@H]2CC(C[C@@H]1[C@H]1O[C@@H]21)OC(=O)C(O)(c1cccs1)c1cccs1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 55 mg/mL (116.42 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.23 mM), Sonication is recommended.
PBS: 50 mg/mL (105.84 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1168 mL10.5838 mL21.1676 mL105.8380 mL
5 mM0.4234 mL2.1168 mL4.2335 mL21.1676 mL
10 mM0.2117 mL1.0584 mL2.1168 mL10.5838 mL
20 mM0.1058 mL0.5292 mL1.0584 mL5.2919 mL
50 mM0.0423 mL0.2117 mL0.4234 mL2.1168 mL
100 mM0.0212 mL0.1058 mL0.2117 mL1.0584 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

Tiotropium BromideTiotropium bromideTiotropiumMuscarinic acetylcholine receptormAChRInhibitorinhibit
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