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Prohibitin ligand 1 (Compound 22i) is a cardioprotective prohibitin ligand that shows in vitro cardioprotective activities at nanomolar concentrations, inducing the pro-survival factor STAT3 phosphorylation [1].
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 25 mg | $1,520 | 10-14 weeks | 10-14 weeks | |
| 50 mg | $1,980 | 10-14 weeks | 10-14 weeks | |
| 100 mg | $2,500 | 10-14 weeks | 10-14 weeks |
| Description | Prohibitin ligand 1 (Compound 22i) is a cardioprotective prohibitin ligand that shows in vitro cardioprotective activities at nanomolar concentrations, inducing the pro-survival factor STAT3 phosphorylation [1]. |
| In vitro | Treatment with Prohibitin ligand 1 (10nM; overnight) results in the phosphorylation of the pro-survival factor STAT3, as demonstrated by Western Blot Analysis [1] using the H9c2 cardiomyocyte cell line. The incubation with a concentration of 10 nM for an overnight period specifically induced STAT3 phosphorylation. |
| Molecular Weight | 306.4 |
| Formula | C20H22N2O |
| Smiles | #N/A |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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