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KIR2DL1 Protein, Human, Recombinant (His & Avi)

Catalog No. TMPK-00461
Synonyms: CD158A, CD158Ankat1, p58.1, KIR2DL1, KIR-K64, NKAT, NKAT-1, KIR221, KIR2DL1/KIR2DS5, cl-42

KIR2DL1 (2DL1, formerly NKAT1, designated CD158a) is a 348 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig-like receptor (KIR) family.KIR2DL1 is a receptor on natural killer (NK) cells for some HLA-C alleles such as w4 and w6. Inhibits the activity of NK cells thus preventing cell lysis.

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KIR2DL1 Protein, Human, Recombinant (His & Avi)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 418.00
500 μg 5 days $ 1,670.00
1 mg 5 days $ 2,800.00
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Biological Description
Technical Params
Product Properties
References and Literature
Description KIR2DL1 (2DL1, formerly NKAT1, designated CD158a) is a 348 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig-like receptor (KIR) family.KIR2DL1 is a receptor on natural killer (NK) cells for some HLA-C alleles such as w4 and w6. Inhibits the activity of NK cells thus preventing cell lysis.
Species Human
Expression System HEK293
Tag C-His-Avi
Accession Number P43626
Synonyms CD158A, CD158Ankat1, p58.1, KIR2DL1, KIR-K64, NKAT, NKAT-1, KIR221, KIR2DL1/KIR2DS5, cl-42
Construction Recombinant Human KIR2DL1 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. It contains His22-Arg242.[Accession |P43626]
Protein Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Molecular Weight The protein has a predicted MW of 27.1 kDa. Due to glycosylation, the protein migrates to 40-52 kDa based on Tris-Bis PAGE result.
Endotoxin Less than 1EU per μg by the LAL method.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability & Storage

-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background KIR2DL1 (2DL1, formerly NKAT1, designated CD158a) is a 348 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig-like receptor (KIR) family.KIR2DL1 is a receptor on natural killer (NK) cells for some HLA-C alleles such as w4 and w6. Inhibits the activity of NK cells thus preventing cell lysis.

References and Literature

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Keywords

KIR2DL1 Protein, Human, Recombinant (His & Avi) CD158A KIR 221 CD158Ankat1 p58.1 KIR2DL1 KIR-K64 NKAT NKAT-1 KIR-221 KIR221 NKAT1 KIR2DL1/KIR2DS5 cl-42 NKAT 1 recombinant recombinant-proteins proteins protein

 

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