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N-Octyl-β-D-thioglucopyranoside (octylthioglucoside, OTG) is a mild nonionic detergent characterized by a thioglycosidic linkage that is used for effective cell lysis or to solubilise integral membrane proteins without denaturing their tertiary or quaternary structure; this property is particularly of use in order to crystallise them for structural studies or to reconstitute them into artificial lipid bilayers for functional assays.
Description | N-Octyl-β-D-thioglucopyranoside (octylthioglucoside, OTG) is a mild nonionic detergent characterized by a thioglycosidic linkage that is used for effective cell lysis or to solubilise integral membrane proteins without denaturing their tertiary or quaternary structure; this property is particularly of use in order to crystallise them for structural studies or to reconstitute them into artificial lipid bilayers for functional assays. |
Synonyms | Octyl-β-D-thioglucopyranoside |
Molecular Weight | 308.43 |
Formula | C14H28O5S |
Cas No. | 85618-21-9 |
Smiles | S(CCCCCCCC)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |
Storage | store at 4°C |
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