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m-PEG-OH (MW 1000)

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Catalog No. TCl-00310
Alias 9004-74-4

m-PEG-OH (MW 1000) serves as a macromolecular initiator, facilitating the synthesis of amphiphilic block copolymers. These copolymers are utilized to create nanoscale micelles for delivering active drugs. When hydrophobic anti-cancer agent Paclitaxel (HY-B0015) is encapsulated within these micelles, it demonstrates enhanced activity against cancer cells compared to free Paclitaxel. Additionally, it predominantly accumulates in tumor tissues, with only limited distribution in healthy organs.

m-PEG-OH (MW 1000)

m-PEG-OH (MW 1000)

😃Good
Catalog No. TCl-00310Alias 9004-74-4
m-PEG-OH (MW 1000) serves as a macromolecular initiator, facilitating the synthesis of amphiphilic block copolymers. These copolymers are utilized to create nanoscale micelles for delivering active drugs. When hydrophobic anti-cancer agent Paclitaxel (HY-B0015) is encapsulated within these micelles, it demonstrates enhanced activity against cancer cells compared to free Paclitaxel. Additionally, it predominantly accumulates in tumor tissues, with only limited distribution in healthy organs.
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10 mgInquiry7-10 days
50 mgInquiry7-10 days
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Product Introduction

Bioactivity
Description
m-PEG-OH (MW 1000) serves as a macromolecular initiator, facilitating the synthesis of amphiphilic block copolymers. These copolymers are utilized to create nanoscale micelles for delivering active drugs. When hydrophobic anti-cancer agent Paclitaxel (HY-B0015) is encapsulated within these micelles, it demonstrates enhanced activity against cancer cells compared to free Paclitaxel. Additionally, it predominantly accumulates in tumor tissues, with only limited distribution in healthy organs.
Alias9004-74-4
Chemical Properties
Molecular Weight1000(Average)
Storage & Solubility Information
Storagekeep away from moisture | store at 4°C

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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