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LPA2 antagonist 2

Name: LPA2 antagonist 2
Brand: TargetMol
SKU: T11875
Price: 58 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T11875Cas No. 36840-10-5

LPA2 antagonist 2 is a selective and potent LPA2 antagonist (IC50: 28.3 nM) with potential anticancer activity, inhibits LPA3, and can be used in the study of cancer.

LPA2 antagonist 2

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Purity: 96.13%

Catalog No. T11875Cas No. 36840-10-5

LPA2 antagonist 2 is a selective and potent LPA2 antagonist (IC50: 28.3 nM) with potential anticancer activity, inhibits LPA3, and can be used in the study of cancer.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$58	In Stock	In Stock
5 mg	$143	In Stock	In Stock
10 mg	$227	In Stock	In Stock
25 mg	$376	In Stock	In Stock
50 mg	$530	In Stock	In Stock
100 mg	$713	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$148	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:96.13%

Appearance:Solid

Color:Green

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COA HPLC HNMR

Product Introduction

Bioactivity

Description	LPA2 antagonist 2 is a selective and potent LPA2 antagonist (IC50: 28.3 nM) with potential anticancer activity, inhibits LPA3, and can be used in the study of cancer.
Targets&IC50	LPA3:13.85 μM, LPA2:28.3 nM
In vitro	LPA2 antagonist 2 has a maximum inhibition rate of 59.0% for LPA1 at 30 µM, indicating its potential to inhibit LPA-mediated biological effects[1].

Chemical Properties

Molecular Weight	380.35
Formula	C₂₀H₁₆N₂O₆
Cas No.	36840-10-5
Smiles	O=C(O)C=CC(=O)NC=1C=CC(=CC1)C2=CC=C(C=C2)NC(=O)C=CC(=O)O
Relative Density.	1.444 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (210.33 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6292 mL	13.1458 mL	26.2916 mL	131.4579 mL
5 mM	0.5258 mL	2.6292 mL	5.2583 mL	26.2916 mL
10 mM	0.2629 mL	1.3146 mL	2.6292 mL	13.1458 mL
20 mM	0.1315 mL	0.6573 mL	1.3146 mL	6.5729 mL
50 mM	0.0526 mL	0.2629 mL	0.5258 mL	2.6292 mL
100 mM	0.0263 mL	0.1315 mL	0.2629 mL	1.3146 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc