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Synonyms: Visceral Adipose-Specific Serpin, Visceral Adipose Tissue-Derived Serine Protease Inhibitor, Vaspin, SERPINA12, Serpin A12, OL-64

| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $80 | 35 days | 35 days | |
| 10 μg | $129 | 35 days | 35 days | |
| 20 μg | $198 | 35 days | 35 days | |
| 50 μg | $390 | 35 days | 35 days | |
| 100 μg | $587 | 35 days | 35 days | |
| 200 μg | $886 | 35 days | 35 days | |
| 500 μg | $1,530 | 35 days | 35 days | |
| 1 mg | $2,180 | 35 days | 35 days |
| Bioactivity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three β-sheets, nine α-helices, and one central loop; the structure is part of the set of distinctive features that are descriptive of Serpin family members. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that Vaspin mRNA expression in visceral fat is positively correlated with BMI and percent of body fat. and could be associated with parameters of obesity, insulin resistance, and glucose metabolism. These findings suggest a potential clinical use for Vaspin in ameliorating certain aberrations seen in the obesity metabolic syndrome. |
| Species | Human |
| Expression System | E. coli |
| Tag | N-GST |
| Accession Number | Q8IW75 |
| Amino Acid | Leu21-Lys414 |
| Construction | Leu21-Lys414 |
| Protein Purity | Greater than 80% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Supplied as a 0.2 μm filtered solution of 50 mM Tris-HCl, 160 mM NaCl, 0.2 mM PMSF, 1 mM DTT, 10% Glycerine, pH 7.2. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Proteins are shipped with blue ice. |
| Synonyms | Visceral Adipose-Specific Serpin, Visceral Adipose Tissue-Derived Serine Protease Inhibitor, Vaspin, SERPINA12, Serpin A12, OL-64 |
| Research Background | Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three β-sheets, nine α-helices, and one central loop; the structure is part of the set of distinctive features that are descriptive of Serpin family members. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that Vaspin mRNA expression in visceral fat is positively correlated with BMI and percent of body fat. and could be associated with parameters of obesity, insulin resistance, and glucose metabolism. These findings suggest a potential clinical use for Vaspin in ameliorating certain aberrations seen in the obesity metabolic syndrome. |
| Molecular Weight | 72 KDa (reducing condition) |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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