Serpin A12 Protein, Human, Recombinant (GST)

Name: Serpin A12 Protein, Human, Recombinant (GST)
Brand: TargetMol
SKU: TMPJ-00262
Rating: 4.5 (1 reviews)

(Synonyms: Visceral Adipose-Specific Serpin, Visceral Adipose Tissue-Derived Serine Protease Inhibitor, Vaspin, SERPINA12, Serpin A12, OL-64) Copy Product Info

Synonyms: Visceral Adipose-Specific Serpin, Visceral Adipose Tissue-Derived Serine Protease Inhibitor, Vaspin, SERPINA12, Serpin A12, OL-64

Catalog No. TMPJ-00262 Copy Product Info

Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three β-sheets, nine α-helices, and one central loop; the structure is part of the set of distinctive features that are descriptive of Serpin family members. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that Vaspin mRNA expression in visceral fat is positively correlated with BMI and percent of body fat. and could be associated with parameters of obesity, insulin resistance, and glucose metabolism. These findings suggest a potential clinical use for Vaspin in ameliorating certain aberrations seen in the obesity metabolic syndrome.

Serpin A12 Protein, Human, Recombinant (GST)

Pack Size	Price	USA Stock	Global Stock
10 µg	$129	35 days	35 days
20 µg	$198	35 days	35 days
50 µg	$390	35 days	35 days
100 µg	$587	35 days	35 days
200 µg	$886	35 days	35 days
500 µg	$1,530	35 days	35 days
1 mg	$2,180	35 days	35 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three β-sheets, nine α-helices, and one central loop; the structure is part of the set of distinctive features that are descriptive of Serpin family members. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that Vaspin mRNA expression in visceral fat is positively correlated with BMI and percent of body fat. and could be associated with parameters of obesity, insulin resistance, and glucose metabolism. These findings suggest a potential clinical use for Vaspin in ameliorating certain aberrations seen in the obesity metabolic syndrome.
Species	Human
Expression System	E. coli
Tag	N-GST
Accession Number	Q8IW75
Amino Acid	Leu21-Lys414
Construction	Leu21-Lys414
Protein Purity	Greater than 80% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 50 mM Tris-HCl, 160 mM NaCl, 0.2 mM PMSF, 1 mM DTT, 10% Glycerine, pH 7.2.
Synonyms	Visceral Adipose-Specific Serpin, Visceral Adipose Tissue-Derived Serine Protease Inhibitor, Vaspin, SERPINA12, Serpin A12, OL-64
Research Background	Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three β-sheets, nine α-helices, and one central loop; the structure is part of the set of distinctive features that are descriptive of Serpin family members. Vaspin is also a unique insulin sensitizing adipocytokine in obesity. A recent publication indicates that Vaspin mRNA expression in visceral fat is positively correlated with BMI and percent of body fat. and could be associated with parameters of obesity, insulin resistance, and glucose metabolism. These findings suggest a potential clinical use for Vaspin in ameliorating certain aberrations seen in the obesity metabolic syndrome.

Chemical Properties

Molecular Weight

72 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.