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RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His)

(Synonyms: TRANCE, TNFSF11, sOdf, RANKL, OPTB2, OPGL, ODF, CD254) Copy Product Info

Synonyms: TRANCE, TNFSF11, sOdf, RANKL, OPTB2, OPGL, ODF, CD254

Catalog No. TMPK-00591 Copy Product Info
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL and RANK are under the tight control of the female sex hormones estradiol and progesterone. RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 28.97 kDa and the accession number is AAC40113.1.
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$587-10 days7-10 days
10 μg$927-10 days7-10 days
20 μg$1487-10 days7-10 days
50 μg$2897-10 days7-10 days
100 μg$4877-10 days7-10 days
200 μg$8837-10 days7-10 days
500 μg$1,9507-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Immobilized Mouse RANKL, His Tag at 1 μg/mL (100 μL/well) on the plate. Dose response curve for Mouse TNFRSF11A, hFc Tag with the EC50 of 4.0 ng/mL determined by ELISA (QC Test).
Description
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL and RANK are under the tight control of the female sex hormones estradiol and progesterone. RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 28.97 kDa and the accession number is AAC40113.1.
Species
Mouse
Expression System
HEK293 Cells
TagC-His
Accession NumberAAC40113.1
ConstructionTyr70-Asp316
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationSupplied as 0.22 μm filtered solution in PBS (pH 7.4).
Stability & StorageIt is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingProteins are shipped with blue ice.
SynonymsTRANCE, TNFSF11, sOdf, RANKL, OPTB2, OPGL, ODF, CD254
Research Background
Chemical Properties
Molecular Weight28.97 kDa (predicted). Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
StorageStore at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His) chemical structure | RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His) molecular weight