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RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His)
(Synonyms: TRANCE, TNFSF11, sOdf, RANKL, OPTB2, OPGL, ODF, CD254) Copy Product InfoSynonyms: TRANCE, TNFSF11, sOdf, RANKL, OPTB2, OPGL, ODF, CD254
Catalog No. TMPK-00591 Copy Product Info
Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL and RANK are under the tight control of the female sex hormones estradiol and progesterone. RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 28.97 kDa and the accession number is AAC40113.1.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 µg | $58 | - | In Stock | |
| 10 µg | $92 | - | In Stock | |
| 20 µg | $148 | - | In Stock | |
| 50 µg | $289 | 7-10 days | 7-10 days | |
| 100 µg | $487 | - | In Stock | |
| 200 µg | $883 | 7-10 days | 7-10 days | |
| 500 µg | $1,950 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Appearance:Lyophilized powder
Color:White
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Bioactivity | Immobilized Mouse RANKL, His Tag at 1 μg/mL (100 μL/well) on the plate. Dose response curve for Mouse TNFRSF11A, hFc Tag with the EC50 of 4.0 ng/mL determined by ELISA (QC Test). |
| Description | Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL and RANK are under the tight control of the female sex hormones estradiol and progesterone. RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 28.97 kDa and the accession number is AAC40113.1. |
| Species | Mouse |
| Expression System | HEK293 Cells |
| Tag | C-His |
| Accession Number | AAC40113.1 |
| Construction | Tyr70-Asp316 |
| Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
| Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
| Formulation | Supplied as 0.22 μm filtered solution in PBS (pH 7.4). |
| Synonyms | TRANCE, TNFSF11, sOdf, RANKL, OPTB2, OPGL, ODF, CD254 |
| Research Background | Receptor activator of nuclear factor x03BA;B (RANK) and its ligand (RANKL) have originally been described for their key roles in bone metabolism and the immune system. Subsequently, it has been shown that the RANKL-RANK system is critical in the formation of mammary epithelia in lactating females and the thermoregulation of the central nervous system. RANKL and RANK are under the tight control of the female sex hormones estradiol and progesterone. |
| Molecular Weight | 28.97 kDa (predicted). Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result. |
| Shipping | Proteins are shipped with blue ice. |
| Storage | It is recommended to store the product under sterile conditions at -70°C or lower. Samples are stable for up to 12 months at -80°C. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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Related Tags: RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His) chemical structure | RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (aa 70-316, His) molecular weight
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