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Pangelin

Name: Pangelin
Brand: TargetMol
SKU: TN2041
Price: 64 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN2041Cas No. 33783-80-1

Pangelin is a natural coumarin exhibiting μM-level inhibition of arachidonic acid-induced platelet aggregation.

Pangelin

🥰Excellent

Purity: 99.99%

Catalog No. TN2041Cas No. 33783-80-1

Pangelin is a natural coumarin exhibiting μM-level inhibition of arachidonic acid-induced platelet aggregation.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$64	-	In Stock
5 mg	$172	-	In Stock
10 mg	$255	-	In Stock
25 mg	$432	-	In Stock
50 mg	$626	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.99%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Pangelin is a natural coumarin exhibiting μM-level inhibition of arachidonic acid-induced platelet aggregation.
In vitro	Pangelin exhibits significant cytotoxicity against four tumor cell lines, with an IC50 range of 8.6-14.6 μg/mL [1].

Chemical Properties

Molecular Weight	286.28
Formula	C₁₆H₁₄O₅
Cas No.	33783-80-1
Smiles	O(C[C@@H](C(C)=C)O)C=1C2=C(C=C3C1C=CO3)OC(=O)C=C2
Relative Density.	no data available
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 40 mg/mL (139.72 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.4931 mL	17.4654 mL	34.9308 mL	174.6542 mL
5 mM	0.6986 mL	3.4931 mL	6.9862 mL	34.9308 mL
10 mM	0.3493 mL	1.7465 mL	3.4931 mL	17.4654 mL
20 mM	0.1747 mL	0.8733 mL	1.7465 mL	8.7327 mL
50 mM	0.0699 mL	0.3493 mL	0.6986 mL	3.4931 mL
100 mM	0.0349 mL	0.1747 mL	0.3493 mL	1.7465 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc