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TargetMol | Compound Library

Microbial Natural Product Library

Catalog No. L6500

Microscopic organisms, commonly known as microorganisms or microbes, are found all around us and even inside our bodies, including a massive range of organisms including bacteria, fungi, viruses, algae, archaea and protozoa. The vast majority of microbes on the earth pose no real threat to humans, plants or animals; in fact they actually work alongside humans to make world go round, aiding decomposition, decay and even helping us to digest our food. Microorganisms are renowned as a prolific source of natural products, making huge contribution to human health. The 1945 and 1952 Nobel Prizes in Physiology or Medicine were awarded for the discovery of penicillin and streptomycin, respectively. Six years later, the 2015 Nobel Prize in Physiology or Medicine was awarded to William C. Campbell and Satoshi Omura, and Youyou Tu for the discovery of avermectins and artemisinin, respectively, therapies that revolutionized the treatment of devastating parasite diseases. Among these four natural products awarded with Nobel Prizes, except for artemisinin, the other three all are microbial natural products. Streptomyces is the important source for natural medicines, the largest antibiotic-producing genus, producing antibacterial (vancomycin and daptomycin, etc.), antifungal (nystatin, amphotericin B, and natamycin), and antiparasitic drugs (Ivermectin), and also a wide range of other bioactive compounds used in other medical treatment, such as anti-cancer drugs (dactinomycin and bleomycin). Microbial Natural Product Library is a unique collection of 489 microbial natural products covering various chemical structures, such as β-lactam, macrolides, aminoglycoside, polypeptides, Chloramphenicol, Tetracycline compounds, Anthraquinone, Benzene derivatives, quinone, Terpenoids, etc. This library can be used in rational drug design, virtual screening, and microbes classification, etc.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L6500

Microbial Natural Product Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 489 microbial natural products for high throughput screening (HTS) and high content screening (HCS);
  • Targets include alpha-glucosidase, beta-lactamase, TNF-alpha, HDAC, PKC, HSP90, etc.;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Antibacterial
Endogenous Metabolite
Antibiotic
Apoptosis
Antifungal
Autophagy
ribosome
Parasite
DNA/RNA Synthesis
Antioxidant
HIV Protease
PKC
Ferroptosis
Topoisomerase
Reactive Oxygen Species
HSV
Mitophagy
Phosphatase
Calcium Channel
MMP
Influenza Virus
Immunology/Inflammation related
NMDAR
GABA Receptor
Microtubule Associated
Amino Acids and Derivatives
Dehydrogenase
PI3K
Nucleoside Antimetabolite/Analog
Caspase
IL Receptor
TNF
Potassium Channel
AChR
HMG-CoA Reductase
Tyrosinase
NO Synthase
ATPase
Wnt/beta-catenin
iGluR
Mitochondrial Metabolism
GluR
COX
mTOR
Akt
Antiviral
HSP
HDAC
NF-κB
Anti-infection
Sodium Channel
ADC Cytotoxin
GPCR
Proteasome
NOS
HCV Protease
p38 MAPK
DNA Alkylator/Crosslinker
LTR
Adenosine Receptor
Cell wall
Histamine Receptor
JNK
Virus Protease
PKA
Tyrosine Kinases
FXR
Adrenergic Receptor
Aryl Hydrocarbon Receptor
DNA gyrase
Glucosidase
ROS
P-gp
SARS-CoV
Aminopeptidase
GPCR19
GluCls
STAT
AMPK
Phospholipase
AhR
Chloride channel
Carbonic Anhydrase
Transaminase
Monocarboxylate transporter
Dopamine Receptor
DNA-PK
Histone Methyltransferase
Src
Integrin
CRM1
Estrogen/progestogen Receptor
Reductase
Aconitase
Lipase
MRP
Estrogen Receptor/ERR
HBV
PARP
Serine/threonin kinase
Glucokinase
ERK
IAP
IRE1
UGT
PDE
Drug Metabolite
P2X Receptor
ABC Transporter
Hexokinase
Hedgehog/Smoothened
JAK
CCR
Cytochromes P450
IGF-1R
Norepinephrine
DUB
Interleukin
Lipid
BCRP
Glutathione reductase
Acyltransferase
Free radical scavengers
Sirtuin
Bcl-2 Family
Casein Kinase
IκB/IKK
ATM/ATR
Beta Amyloid
CRISPR/Cas9
5-HT Receptor
PLK
HIF
Adenosine Deaminase
Complement System
Syk
DNA Methyltransferase
NOD
Thrombin
HIF/HIF Prolyl-Hydroxylase

Keywords